Précis: Ultrasound cyclo plasty (UCP) using high-intensity focused ultrasound is an effective and safe procedure in lowering intraocular pressure (IOP) in patients with glaucoma, even in those with high myopia.Purpose: This study aimed to evaluate the efficacy and safety of UCP in glaucoma patients with high myopia.Materials and Methods: In this retrospective, single-center study, we enrolled 36 eyes divided into 2 groups based on axial length: group A ( ≥ 26.00 mm) and group B (< 26.00 mm). We collected data about visual acuity, Goldmann applanation tonometry, biomicroscopy, and visual field before the procedure and at 1, 7, 30, 60, 90, 180, and 365 days after the procedure.Results: Mean IOP significantly decreased in both groups after treatment (P < 0.001). Mean IOP reduction from baseline to the last visit was 9.8 ± 6.6 mmHg (38.7%) in group A and 9.6 ± 6.3 mmHg (34.8%) in group B (P < 0.001). Mean IOP at the last visit was 15.8 ± 4.1 mmHg in the myopic group and 18.1 ± 5.6 mmHg in the non-myopic one. Regarding the number of IOP-lowering eyedrops being taken by our patients, statistically significant differences were found between groups A and B neither at baseline (2.8 ± 0.9 and 2.6 ± 1.0; P = 0.568) nor 1 year after the procedure (2.5 ± 1.1 and 2.6 ± 1.1; P = 0.762). No major complications occurred. All minor adverse events resolved within a few days.
Conclusion:UCP seems to be an effective and well-tolerated strategy to lower IOP in glaucoma patients with high myopia.