Abstract:Background: Physical exercise and activity status may modify the effect of fat mass- and obesity-associated (FTO) genotype on body weight and obesity risk. To understand the interaction between FTO’s effect and physical activity, the present study investigated the effects of high and low intensity exercise on FTO mRNA and protein expression, and potential modifiers of exercise-induced changes in FTO in healthy-weighted individuals. Methods: Twenty-eight untrained males and females (25.4 ± 1.1 years; 73.1 ± 2.0… Show more
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