High incidence of treatment failure with vincristine, etoposide, epirubicin, and prednisolone chemotherapy with successful salvage in childhood Hodgkin disease
Abstract:Background and Procedure
In an attempt to further reduce the long‐term toxicity of chemotherapy for childhood Hodgkin disease (HD), the Australian and New Zealand Children's Cancer Study Group between 1990 and 1996 enrolled 53 children with biopsy‐proven and imaging‐staged HD into a chemotherapy‐only treatment regimen using 5–6 courses of vincristine, etoposide, epirubicin, and prednisolone (VEEP).
Results
There were 23 events in these children with 3 progressive disease (PD), 8 partial remissions (PR), and 12… Show more
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