High Incidence of Lymph Node Metastasis in Major Salivary Gland Cancer

Stennert, E.; Kisner, Dilek; Jungehuelsing, Markus; Guntinas‐Lichius, Orlando; Schröder, U.; Eckel, Hans Edmund; Klußmann, Jens Peter

doi:10.1001/archotol.129.7.720

Cited by 188 publications

(142 citation statements)

References 22 publications

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“…Some surgeons recommend removing the deep lobe any time the parotid area nodes are involved with metastatic cancer [3,28,29]. However, this may ignore other important information necessary for optimal decision making.…”

Section: Preoperative Discussionmentioning

confidence: 99%

Deep lobe parotidectomy—why, when, and how?

Olsen

Quer

Bree

et al. 2017

Eur Arch Otorhinolaryngol

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Section: Preoperative Discussionmentioning

confidence: 99%

Deep lobe parotidectomy—why, when, and how?

Olsen

Quer

Bree

et al. 2017

Eur Arch Otorhinolaryngol

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“…Stennert et al found a high incidence of occult metastatic disease in the lymph nodes of the deep lobe and recommended a complete parotidectomy in every case of primary parotid gland carcinomas. 8 In a study with 128 mucoepidermoid carcinomas, most recurrences were detected in the parotid bed, pointing to the need for adequate control, at least at the site of the primary tumor. 12 In our experience, however, a malignant tumor of the parotid gland does not necessarily have any clinical (pain, facial palsy) or imaging signs of malignancy (enlarged neck nodes, blurred lesion margins, elastographic ''garland'' sign 13 ).…”

Section: Discussionmentioning

confidence: 99%

Unexpected Detection of Parotid Gland Malignancy during Primary Extracapsular Dissection

Mantsopoulos

Velegrakis

Iro

2015

Otolaryngol.--head neck surg.

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Objective. To evaluate the oncologic and functional outcome in cases in which a false preoperative working hypothesis ''benign parotid tumor'' led to a primary extracapsular dissection being performed rather than a traditional, more radical surgical modality.Study Design. Case series with chart review.Setting. Academic tertiary referral center.Subjects and Methods. The records of all patients treated for malignant tumors of the parotid gland between 2006 and 2012 were retrospectively studied. Patients were excluded from our study sample for insufficient data or if their histories indicated manifestation of malignant tumors without primary parotid origin (squamous cell carcinomas, lymphomas, melanomas), revision surgery, as well as concomitant or past malignant tumors. Consequently, a total of 29 patients with 30 primary malignant tumors of the parotid gland formed our study sample (14 men, 15 women; male:-female ratio, 0.93:1; mean age, 55.4 years; range, 14-85 years).Results. Of 30 cases, 22 had low-grade tumors. Further tumor cells were detected in only the histology specimens of the parotid in 3 of the 25 cases treated subsequently with completion parotidectomy. Five patients received adjuvant radiation. Five-year disease-specific survival was 100%; local disease control was 96.6%. Of 30 cases, 28 had HouseBrackmann I after tumor treatment; the other 2 cases had a slight paralysis (House-Brackmann II). Conclusion.Beginning with the ''false'' working hypothesis and performing an extracapsular dissection in unsuspected cases seems to have no adverse impact on patients' survival and postoperative quality of life in cases in which definitive histology reveals malignancy.

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“…1,18,29,31 Myoepithelial carcinomas may be characterised by nodal spread and these may be addressed surgically as well. 32 Chemotherapy has no effectiveness against these tumours. 1,18,28,29,31 The tumour in this case was well circumscribed, had a soft tissue density, and was partially surrounded by reactive bone.…”

Section: Discussionmentioning

confidence: 99%

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

Hayward

Yoo

Lee

et al. 2014

Neuro-Ophthalmology

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Myoepitheliomas are rare tumours that originate from glandular tissues such as the parotid or salivary glands, and less commonly from soft tissues of the head, neck, and other parts of the body. Intraorbital myoepitheliomas generally arise from the lacrimal gland. Intracranial myoepitheliomas are rare. We report a myoepithelioma of the orbital apex that did not originate from the lacrimal gland. It extended to the middle cranial fossa from the orbital apex and involved the dura and adjacent bone. A diagnostic biopsy via a lateral orbitotomy preceded resection. We review the natural course and histopathology of myoepithelial neoplasms, the surgical nuances of approaching an orbital apex tumour with maximal functional preservation, and the optimal management practices of these rare lesions.

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High Incidence of Lymph Node Metastasis in Major Salivary Gland Cancer

Abstract: We found a high incidence of lymph node metastasis from major salivary gland cancers. Neck dissections should be considered as an integral part of the surgical approach in patients with major salivary gland cancer, especially if no postoperative radiation therapy is planned.

Cited by 188 publications

References 22 publications

Deep lobe parotidectomy—why, when, and how?

Deep lobe parotidectomy—why, when, and how?

Unexpected Detection of Parotid Gland Malignancy during Primary Extracapsular Dissection

Myoepithelioma of the Orbital Apex and Middle Cranial Fossa: Case Report and Review of the Literature

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