1977
DOI: 10.1016/0091-6749(77)90148-8
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High incidence of horse serum protein allergy in various autoimmune disorders

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Cited by 5 publications
(6 citation statements)
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“…It is used for blood flow imaging in the heart, liver and brain [4,18,19] and may be used in veterinary science and medicine in the future. However, Optison ® also has the possibility of causing anaphylaxis in animals since a major component of this compound is human albumin microspheres [9,13]. In this paper, we report two dogs with an AR to Optison ® out of a group of 26 dogs given intravenous injections of this agent for another purpose [21].…”
mentioning
confidence: 98%
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“…It is used for blood flow imaging in the heart, liver and brain [4,18,19] and may be used in veterinary science and medicine in the future. However, Optison ® also has the possibility of causing anaphylaxis in animals since a major component of this compound is human albumin microspheres [9,13]. In this paper, we report two dogs with an AR to Optison ® out of a group of 26 dogs given intravenous injections of this agent for another purpose [21].…”
mentioning
confidence: 98%
“…Major cardiovascular responses to AR are an increase in heart rate, systemic hypotension and a fall in Q . T and DO 2 to tissues [3,9,15]. Potential pulmonary responses are a rise in PVR, bronchoconstriction and sometimes pulmonary edema [1,6,8,14].…”
Section: A /Qmentioning
confidence: 99%
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“…The horse genome sequence will also assist trait mapping of specific diseases within modern breeds of horses and contribute to a better understanding of medical conditions such as influenza, arthritis and allergies that are shared by horses and humans (Ring et al 1977; Livesay et al 1987; Dolvik & Klemetsdal 1996). Many drugs are used to improve health and treat disease for both species and given the roles of CES in drug metabolism (Redinbo and Potter 2005), lung physiology (Ruppert et al 2006) and xenobiotic, insecticide, lipid and cholesterol metabolism (see Imai 2006), studies of the genetics and biochemistry of horse CES will contribute to an improved understanding of the contribution of genetics to these important metabolic processes in the horse.…”
Section: Discussionmentioning
confidence: 99%
“…purposes. Though the T helper-specific human T4 antigen had already been described by 1979(Reinherz et al 1979, a systemic study of its usefulness as target for immuno therapies became possible only when a monoclonal antibody against its murine homoiogue, L3T4, was made available (Dialynas et al 1983). As elsewhere reported in this volume, CD4 antibodies have become a major analytical and therapeutic tool to dissect and influence the immune response in vivo.…”
Section: Introductionmentioning
confidence: 99%