High Incidence of Hepatitis B Virus Infection in Hemodialysis Patients at Sanglah General Hospital and It’s Risk Factors

Purnamasidhi, Cokorda Agung Wahyu; Mariadi, I Ketut; Wibawa, I Dewa Nyoman; Kandarini, Yenny

doi:10.24871/1732016155-161

Cited by 4 publications

(13 citation statements)

References 26 publications

(39 reference statements)

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“…Some studies reported that longer duration of HD was a risk factor associated with nosocomial infections [16][17][18][19], while a positive correlation was determined between HABSI and diabetes, number of HD sessions, and length of hospital stay [12]. Risk for a HABSI increased significantly with HbA1c levels above 7% [12].…”

Section: Discussionmentioning

confidence: 99%

“…Risk for a HABSI increased significantly with HbA1c levels above 7% [12]. There were studies which showed a significant relationship between nosocomial infections and age of patients [15,16,18], with HBV infections being more common in relatively younger individuals (mean age: 39.2 ± 14.6 years), while there was a strong relationship between HCV infections and relatively older age group (mean age: 55 ± 12 years) [16,18]. A positive history and number of blood transfusions were both https://doi.org/10.1371/journal.pone.0234376.t002…”

Section: Discussionmentioning

confidence: 99%

“…The quality rating of majority of the studies in this review was fair [11][12][13][14][15][16], while three studies had a maximum score, and were rated as good quality studies [17][18][19]. Table 1 shows the detail quality scoring of the studies.…”

Section: Evaluation Of Study Qualitymentioning

confidence: 99%

“…Two studies were conducted in the United States (US) [11,12], and one each in of the China [17], South Korea [13], Canada [14], Taiwan [15], Indonesia [16], Iraq [18], and India [19]. Five studies utilized cross-sectional [12,13,15,16,18] study designs, one was retrospective cohort and case control study [11], and two were longitudinal or prospective studies [14,19]. Tang et al 2016, adopted a mixed study design (incorporating both cross-sectional and longitudinal study designs) [17].…”

Section: Characteristics Of the Selected Studiesmentioning

confidence: 99%

“…significantly associated with HBV or HCV infection [16,19]. Moreover, patients with multiple co-morbidities, with more catheter sites (two or more), low hemoglobin concentration, low white blood cells count, and longer duration of catheterization were found to be at more risk of developing nosocomial infections [17].…”

Section: Plos Onementioning

confidence: 99%

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Risk factors associated with nosocomial infections among end stage renal disease patients undergoing hemodialysis: A systematic review

2020

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Evaluation Of Study Qualitymentioning

confidence: 99%

Section: Characteristics Of the Selected Studiesmentioning

confidence: 99%

Section: Plos Onementioning

confidence: 99%

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Risk factors associated with nosocomial infections among end stage renal disease patients undergoing hemodialysis: A systematic review

2020

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Hepatitis C Seroconversion Remains High among Patients with Regular Hemodialysis: Study of Associated Risk Factors

Dharmesti

Wibawa

Kandarini

2022

International Journal of Hepatology

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Background/Aims. Hemodialysis patients have a higher risk of hepatitis C compared to the general population. The burden of hepatitis C infection among hemodialysis patients is substantial and was estimated to rise constantly. This study is aimed at determining the frequency of HCV seroconversion and associated risk factors among hemodialysis patients in our unit. Methods. An analytical cross-sectional study involving patients from 2 dialysis units (1 referral hospital and 1 private dialysis unit) in Denpasar, Bali, Indonesia, from January 2020 to December 2021. We evaluated age, gender, duration of hemodialysis, vascular access, history of transfusion, history of surgery, diabetes mellitus, hepatitis B, human immunodeficiency virus (HIV) infection, and type of dialyzer as possible risk factors of hepatitis C seroconversion among hemodialysis patients. Results. A total of 338 hemodialysis patients were enrolled in this study. We found hepatitis C seroconversion in 94 patients (27.8%), all of which occurred after regular dialysis was started. Vascular access type (OR 42.07, 95% CI 5.757–307.472) and dialyzer reuse (OR 8.324, 95% CI 4.319–16.044) were showing a statistically significant association with hepatitis C seroconversion. A separate analysis on each dialysis unit found common evidence that the duration of dialysis was significantly associated with hepatitis C infection among hemodialysis patients. Conclusion. Hepatitis C seroconversion among dialysis patients remains high. Factors related to the dialysis procedure itself played a major role in transmitting the virus.

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Comparison of different rapid screening tests and ELISA for HBV, HCV, and HIV among healthy blood donors and recipients at Jibla University Hospital Yemen

Al-Matary¹,

Gashaa

2022

JMedLife

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Blood transfusion is associated with many risks, especially exposure to blood transfusion-transmitted infections considered one of the main causes of death worldwide, including hepatitis B (HBV) and C virus (HCV) and human immunodeficiency virus (HIV). The threat posed by blood-borne pathogens is disproportionately high, especially in developing countries, so there is a need for continuous monitoring of blood transfusions to prevent transmitting diseases. Rapid diagnostic immunochromatographic technique (ICT) methods are the most widely used methods in developing countries, although ELISA and molecular testing are considered more accurate worldwide. Therefore, the study aimed to compare the analytical sensitivity between rapid tests and the ELISA method for detecting HBV, HCV, and HIV infection among blood donors. Four hundred (400) blood donor samples were tested using the Rapid Test Kits (INTEC, SD, ABON, and CLUN), and the ELISA method was used as a confirmatory test. Out of 400 blood samples tested for viral infection, HBV, HCV, and HIV were detected in 8, 10, and 2 samples, respectively, using the ELISA technique. This study observed that the rate of sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV), in addition to determining the diagnostic accuracy rate and error rate for all rapid diagnostic kits in detecting HBV, HCV and HIV are less accurate and associated with more false negatives compared to the ELISA technique. This study showed a significant difference in sensitivity between ELISA and rapid diagnostic immunochromatographic technique (ICT) groups; therefore, rapid diagnosis is not suitable for testing the quality of infectious markers for blood donors.

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High Incidence of Hepatitis B Virus Infection in Hemodialysis Patients at Sanglah General Hospital and It’s Risk Factors

Cited by 4 publications

References 26 publications

Risk factors associated with nosocomial infections among end stage renal disease patients undergoing hemodialysis: A systematic review

Risk factors associated with nosocomial infections among end stage renal disease patients undergoing hemodialysis: A systematic review

Hepatitis C Seroconversion Remains High among Patients with Regular Hemodialysis: Study of Associated Risk Factors

Comparison of different rapid screening tests and ELISA for HBV, HCV, and HIV among healthy blood donors and recipients at Jibla University Hospital Yemen

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