High heating efficiency of interactive cobalt ferrite nanoparticles

Abstract

Cobalt ferrite nanoparticles (CFNPs) are emerging as a potential candidate for biomedical applications, such as magnetic hyperthermia therapy (MHT), due to their high saturation magnetisation (M S) and effective magnetic anisotropy constant (K eff) at the nanoscale. For MHT, heating efficiency depends considerably on applied AC magnetic field, particle diameter, and inter-particle interaction. Our study is aimed at developing a superparamagnetic nanosystem based on CFNPs with enhanced specific absorption rate (SAR) for advanced MHT. The CFNPs were synthesised using thermal decomposition of organometallic precursors. Transmission electron microscopy reveals a narrow size distribution of the CFNPs, with average particle sizes of 8 and 11 nm. Magnetic measurements showed high values of M S (~70 emu g−1) and K eff (2–3 × 106 erg cm−3). The ferromagnetic behaviour and strong interaction between particles at room temperature are also observed. Large SAR values of the CFNPs are achieved, which are superior to those reported previously in the literature. The high heating efficiencies of the present CFNPs make them a promising candidate for advanced MHT.

Structural, magnetic and hyperthermia properties and their correlation in cobalt-doped magnetite nanoparticles

“…Magnetic nanoparticles (MNPs) have triggered the attention of researchers in biomedical applications, such as magnetic resonance imaging, magnetic separation, drug delivery, biosensing, and as heat mediators in magnetic hyperthermia (MH)an effective approach to eliminate cancer in conjunction with chemotherapy and radiation. [1][2][3][4] In MH application, the heating efficiency of MNPs under an ac magnetic eld (ACMF), dened by the specic loss power (SLP) or the specic absorption rate (SAR), depends on many factors such as particle size (D), saturation magnetization (M S ), magneto-crystalline anisotropy constant (K), etc.4-9…”

“…The MNPs, including spinel ferrites, have been synthesized by various chemical methods such as co-precipitation, [9][10][11][12] hydrothermal, [13][14][15][16] thermal decomposition, [4][5][6][7][8]17,18 etc. Cation distribution, particle size, size distribution and consequently the magnetic properties and application of MNPs are inuenced by the synthesis methods.…”

Structural, magnetic and antibacterial studies of gadolinium doped cobalt ferrite nanoparticles synthesized at low temperature

“…Cobalt ferrite possesses reasonably high electrical resistivity, coercivity, moderate saturation magnetisation, large magnetostriction (λ s ∼ 110 × 10 −6 ) and a stable ferromagnetic phase even at higher temperatures, making it suitable for sensor and actuator applications [1][2][3][4][5][6][7]. However, several intrinsic and extrinsic parameters such as cation distribution, crystallite size, chemical composition, uniform grain size, porosity, and method of preparation play key role in tailoring the electrical, magnetic, and optical properties of these cobalt ferrites.…”