High Grade Leiomyosarcoma of the Testes

Bakhshi, Girish D.; Wankhede, Kishor R.; Tayade, Mukund B; Shenoy, Sachin S.; Mundhe, Shankar T.; Patel, Chintan

doi:10.4081/cp.2011.e122

Cited by 6 publications

(6 citation statements)

References 9 publications

(10 reference statements)

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“…Primary leiomyosarcoma in testis was an unusual finding with only some reported cases in published articles (5). Said that, to date, only 15 patient with primary leiomyosarcoma in testis have been reported (3). Reported cases with primary leiomyosarcoma in testis had the average age of 50 years which is compatible with our case.…”

Section: Discussionsupporting

confidence: 87%

“…Leiomyosarcoma in testis is an uncommon tumor which might happen after radiotherapy, chronic inflammation, or anabolic steroids use for long time. However, in absent of risk factors, it is seldom found (3). Here we report a patient with primary leiomyosarcoma in testis, which was thought to derive from normal testis organ include smooth muscle cells, such as blood vessels or seminiferous tubules' contractile cells.…”

Section: Introductionmentioning

confidence: 89%

See 1 more Smart Citation

Primary Testis Leiomyosarcoma: A Case Report

Nazar¹,

Shabanzadeh²,

Moghadam-Ahmadi³

et al. 2021

Iran J Pathol

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Scan to discover onlinePrimary leiomyosarcoma in testis is an uncommon tumor with few cases reported. It generally develops after radiotherapy or long-term taking anabolic steroid medication. We report a 53-year-old male patient with primary testis leiomyosarcoma who presented with painless testicular enlargement without any known predisposing factors. Ultrasound revealed a large heterogeneous left testicular solid lesion. Alpha-fetoprotein (AFP) and beta-human chorionic gonadotrophin (beta-HCG) levels in serum were normal. Left radical orchidectomy following with histology assessment established a diagnosis of primary leiomyosarcoma of testis. No data of cancer metastasis was established. The patient didn't receive any adjuvant therapy. There wasn't any evidence of recurrence after 1 year follow-up. Leiomyosarcoma must be one of the differential diagnoses of seronegative tumors in testis. The motivation for this paper is the extreme infrequency of the situation and the differential diagnosis by all expansive inguinoscrotal tumors.

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Section: Discussionsupporting

confidence: 87%

Section: Introductionmentioning

confidence: 89%

Primary Testis Leiomyosarcoma: A Case Report

Nazar¹,

Shabanzadeh²,

Moghadam-Ahmadi³

et al. 2021

Iran J Pathol

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“…It seems to be not different from other malignant testicular tumors. Tumor markers (AFP, β-hCG and LDH) used in the previously reported cases were almost within the normal range, except two cases: one case with an elevated LDH [14] and the second with elevated β-hCG [16]. This case had an elevated LDH.…”

Section: Discussionmentioning

confidence: 65%

“…Although, adjuvant treatment chemotherapy and radiotherapy may be used for intratesticular leiomyosarcoma with high stage [14]. This case was treated with HIO without any adjuvant treatment and after 24 months of follow-up the patient was free of disease.…”

Section: Discussionmentioning

confidence: 97%

Primary intratesticular leiomyosarcoma in a 78-year-old male

Hmida¹,

Mallat²,

Othmen³

et al. 2014

IJCRI

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International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties.Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. Primary leiomyosarcoma of the testis is a rare entity with only less than 20 cases were reported. The standard therapy is difficult to recommend because of the rarity of this tumor. Case Report: We reported a case of primary intratesticular leiomyosarcoma in a 78-yearold male with unremarkable past medical history. The patient was presented within isolated testicular enlargement. Ultrasound revealed a large solid, homogenous and hyper echoic mass of the right testicle. Lactate dehydrogenase (LDH) was elevated, however, serum alphafetoprotein (AFP) and beta-human chorionic gonadotropin (β-hCG) were within normal limits. A right radical orchidectomy was performed. The diagnosis of primary leiomyosarcoma of testis was confirmed by histopathology. Conclusion:The primary leiomyosarcoma of testis is a rare diagnosis which should be one of the differential diagnoses of testicular mass with normal tumor markers.

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“…We cannot deny the incidental concomitance of the diseases. However, chronic inflammation is suggested to be a risk factor for testicular LMS in some case reports ( 8 - 11 ), and further study may thus be needed to reveal the causal relationship between LMS and chronic bowel inflammation.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Colonic Leiomyosarcoma in Association with Ulcerative Colitis

et al. 2016

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Ulcerative colitis (UC) is known to be associated with an increased risk of colorectal cancer. However, the occurrence of non-epithelial malignancies is uncommon. An elevated lesion in the descending colon was found in a 51-year-old woman with a 30-year history of UC. Despite tumor progression, repeated biopsies showed no cancerous findings. Because the lesion was highly suspected to be a malignant tumor, a partial colectomy was performed. The pathological diagnosis was leiomyosarcoma. Leiomyosarcoma of the gastrointestinal tract is rare, and this is only the third known case reported in patients with UC.

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High Grade Leiomyosarcoma of the Testes

Cited by 6 publications

References 9 publications

Primary Testis Leiomyosarcoma: A Case Report

Primary Testis Leiomyosarcoma: A Case Report

Primary intratesticular leiomyosarcoma in a 78-year-old male

A Rare Case of Colonic Leiomyosarcoma in Association with Ulcerative Colitis

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