High frequency of Gilbert's syndrome in ETV6/RUNX1-positive childhood acute lymphoblastic leukemia (ALL): Implications for etiology.

Can Gilbert's syndrome mitigate chronic lymphocytic leukemia?

“…The impact of GS on the course of cancers [3] and hematological malignancies in particular remains uncertain. The higher incidence of GS has been reported in childhood acute leukemia (14–20%) [5] , [6] , 7 , but no differences in outcome were found in patients with GS [7] . GS has also been associated with excessive toxicity of anticancer drugs in childhood acute lymphoblastic leukemia [8] , but improved outcomes in adult patients with Hodgkin lymphoma [9] .…”

Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert's syndrome

“…Some reports suggest that GS might be a risk factor of cancer [ 5 , 6 ]. GS with coexisting hematological malignancies including AML has been reported in individuals, but the incidence of hematological malignancy in GS is still unknown [ 1 ].…”