High-frequency endoluminal ultrasonography for staging transitional cell carcinoma of the bladder

Horiuchi, Kazutaka; Tsuboi, Narumi; Shimizu, Hiroyuki; Matsuzawa, Ichiro; Kimura, Go; Yoshida, Kazuhiro; Akimoto, Masao

doi:10.1016/s0090-4295(00)00646-4

Cited by 20 publications

(21 citation statements)

References 7 publications

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“…21 The difficulty of making a distinction between stage T2a and stage T2b tumors was experienced with endoluminal ultrasonography as well. 16 These results show that the CL and H/CL cutoff values we have determined have higher sensitivity (81% for both) and specificity (75% for CL and 88.9% for H/CL) for differentiating tumor stages lower than T2a, higher than the aforementioned studies.…”

Section: Discussionmentioning

confidence: 44%

“…15 However, the technique has the inherent limitations of an inability to evaluate the depth of invasion of large tumors having a broad base because of the lack of penetration of the ultrasound beam and an inability to visualize the tumor base located in the bladder neck. 15,16 In a previous study by Ukimura et al, 17 it was reported that extraprostatic extension of prostatic tumors could be predicted by determination of the CL with the fibromuscular rim. The authors investigated whether the CL of the lesion with the fibromuscular rim correlated with extraprostatic extension.…”

Section: Discussionmentioning

confidence: 98%

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A New Parameter for Staging Bladder Carcinoma

Özden

Turgut

Yeşil

et al. 2007

Journal of Ultrasound in Medicine

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Objective. The purpose of this study was to investigate the value of tumor-bladder wall contact length (CL), tumor height (H), and height-to-length ratio (H/CL) for preoperative staging of bladder carcinoma. Methods. Fifty-seven patients with bladder tumors underwent suprapubic ultrasonography preoperatively, and the CL of the tumor with the bladder wall and H in the bladder lumen were measured. The CL, H, and H/CL values were correlated with the wall invasion determined by histopathologic analysis of the cystectomy material. Invasion was staged according to the TNM classification system. Results. Statistically significant differences were found for CL (P < .001) and H/CL (P = .001) between the superficial and invasive tumor groups. These parameters were also effective for differentiating superficial or deep muscle invasion. A CL of greater than 41.5 mm and an H/CL of less than 0.605 were calculated as cutoff values for differentiating superficial and invasive tumors. Height had no value for determining invasion. Conclusions. The ultrasonographic measurements of CL of the tumor with the bladder wall and H/CL may be useful for staging bladder carcinoma by verification of these findings in larger groups of patients.

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Section: Discussionmentioning

confidence: 44%

Section: Discussionmentioning

confidence: 98%

A New Parameter for Staging Bladder Carcinoma

Özden

Turgut

Yeşil

et al. 2007

Journal of Ultrasound in Medicine

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“…Although transurethral ultrasound and endoluminal ultrasound (ELUS) are good tools for the staging of bladder tumors that are confined to the bladder wall [3], they are limited by low resolution. To get better images with higher resolution, Horiuchi K used high-frequency ELUS for the staging of bladder tumors [4]. Unfortunately, high-frequency ELUS has a limited depth of penetration, which makes it difficult to evaluate the depth of invasion of tumors larger than 2 cm in size with a broad base [4].…”

Section: Introductionmentioning

confidence: 99%

“…To get better images with higher resolution, Horiuchi K used high-frequency ELUS for the staging of bladder tumors [4]. Unfortunately, high-frequency ELUS has a limited depth of penetration, which makes it difficult to evaluate the depth of invasion of tumors larger than 2 cm in size with a broad base [4]. In addition, ELUS is a rigid instrumentation and it can not provide good images for bladder tumors based in the bladder neck and intradiverticulum [5].…”

Section: Introductionmentioning

confidence: 99%

A New Tool for Distinguishing Muscle Invasive and Non-Muscle Invasive Bladder Cancer: The Initial Application of Flexible Ultrasound Bronchoscope in Bladder Tumor Staging

Zhang

Wang

et al. 2014

PLoS ONE

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ObjectivesTo validate the flexible ultrasound bronchoscope (FUB) as a tool in distinguishing muscle invasive and non-muscle invasive bladder tumors.Materials and MethodsFrom June 2010 to April 2012, 62 patients (11 female and 51 male) with 92 bladder urothelial carcinoma were treated in our study. The mean (±SD) patient age was 64.0±12.5 years old (ranged from 22 to 87). Clinical T stage was assessed by FUB at first in operating room, then immediately initial diagnostic transurethral resection (TUR) was performed. A second TUR would be done 2–4 weeks after initial TUR when the latter was incomplete (in large and multiple tumours, no muscle in the specimen) or when an exophytic high-grade and/or T1 tumour was detected. And radical cystectomy would be performed for the patients who were diagnosed with muscle-invasive tumors. FUB staging and initial TUR staging, final pathological results were compared.ResultsIn ultrasonic images, the normal muscle layer of bladder wall could be clearly distinguished into three layers, which were hyperechogenic mucosa, hypoechogenic muscle and hyperechogenic serosal. For non-muscle invasive tumors, the muscle layers were continuous. And distorted or discontinuous muscle layers could be seen in muscle-invasive case. The overall accuracy (95.7%) and the specificity of muscle invasion detection of FUB (98.8%) were comparable to TUR (overall accuracy 90.2% and specificity 100%), but sensitivity of muscle invasion detection of FUB was significantly higher than initial TUR (72.7%VS18.2%). Moreover, the tumor's diameter could not affect the FUB's accuracy of muscle invasion detection. For tumors near the bladder neck, FUB also showed the similar validity as those far from bladder neck.ConclusionsTo conclude, the flexible ultrasound bronchoscope is an effective tool for muscle invasion detection of bladder tumor with ideal ultrasonic images. It is an alternative option for bladder tumor staging besides TUR. It might have the potentiality to change the bladder diagnostic strategy.

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“…[1][2][3][4] The superior resolution of this method compared with conventional ELUS not only allows superficial bladder tumors to be distinguished from those with muscle invasion but also allows stage T a tumors to be distinguished from stage T 1 tumors.…”

Section: Introductionmentioning

confidence: 99%