High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction

Kei, Joseph; Brazel, Bronwyn; Crebbin, Kimberley; Richards, Amber; Willeston, Natalie

doi:10.1016/j.ijporl.2006.09.013

Cited by 10 publications

(11 citation statements)

References 26 publications

(44 reference statements)

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“…studied DPOAEs in conventional and ultra-high frequencies in children with and without middle-ear dysfunction. 11 Their results showed a significant reduction in DPOAE amplitude and signal-to-noise ratio at 1, 1.5, 2, 3, 4, 6, 8 and 13 kHz for the ‘fail immittance’ group when compared to the ‘pass immittance’ group.…”

Section: Discussionmentioning

confidence: 92%

“…was higher than that reported in the present study for both the control and clinical groups. 11 The differences in DPOAE amplitude between the two studies could be attributed to the differences in participants’ age ranges in the two studies; that is, children versus adult participants.…”

Section: Discussionmentioning

confidence: 99%

“…Distortion product OAEs at ultra-high frequencies were studied in children with and without middle-ear effusion. 11 The findings revealed that the effect of middle-ear effusion in the ultra-high frequency region was not as severe as that in the lower frequency region. In that study, all subjects had a hearing threshold within 20 dB HL from 0.5 to 8 kHz, and DPOAEs were measured only at one level of the primary tones.…”

Section: Introductionmentioning

confidence: 92%

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Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

et al. 2019

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BackgroundDetection and valid measurements of distortion product otoacoustic emissions are not influenced by cochlear status alone, but also by middle-ear status. There is a need to understand the use of ultra-high frequency distortion product otoacoustic emissions in cases of abnormal distortion product otoacoustic emission findings for conventional frequencies related to the middle-ear condition.MethodThe present study investigated distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies in: 37 adults with chronic suppurative otitis media (clinical group) and 37 adults with normal hearing sensitivity (control group).ResultsThere were significant reductions in distortion product otoacoustic emission amplitude and mean signal-to-noise ratio in the clinical group compared to the control group, especially for conventional frequencies.ConclusionThere was a significant reduction in the rate of ears with measurable distortion product otoacoustic emissions in the clinical group, especially for conventional frequencies. The effect of chronic suppurative otitis media was more pronounced in the conventional frequency range compared to the smaller effect seen in the ultra-high frequency range.

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Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 92%

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Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

et al. 2019

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“…DPOAEs are clinically useful in identifying middle ear effusion in infants and children (Choi, Pafitis, Herer, Zalzal, & Patel, 1999;Kei, Brazel, Crebbin, Richards, & Willeston, 2007;Yeo, Park, Park, & Suh, 2002). Two studies using older children (over 5 years of age) concluded that DPOAEs better differentiated between normal and diseased ears (Akdogan & Özkan, 2006;Thakur et al, 2013).…”

Section: Evoked Otoacoustic Emissionsmentioning

confidence: 99%

Diagnosing conductive dysfunction in infants using wideband acoustic immittance: development and validation of predictive models

Myers¹

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Background. Infants with early onset of otitis media have greater risk of recurrent and chronic infections that can affect language and development. Diagnostic tools able to quickly and accurately identify middle ear pathology early in infancy could help to facilitate timely intervention for these children.Wideband acoustic immittance (WAI) is an emerging technology for assessing middle ear function with significant advantages over established clinical tests such as tympanometry. WAI does not require pressurization of the ear canal, and is a high-resolution test, measuring middle ear function over a wider frequency range than is possible with tympanometry. Preliminary studies in infants have shown promising results, but further research assessing the diagnostic performance of WAI is needed. Also, the large amount of data generated by WAI can make results difficult to interpret. Research into suitable quantitative techniques to analyse results is still in its infancy. Prediction models are an attractive method for analysis of multivariate data as they can provide individualized probabilities that an infant has middle ear dysfunction. A clinically useful prediction model must be able to accurately discriminate between normal ears and those with middle ear dysfunction, and be well calibrated (i.e., give accurate predictions). However, the number of variables generated by WAI can cause issues with overfitting when developing multivariate models. An overfitted model will accurately describe the data it was developed on, but is likely to perform poorly when applied to new samples. Some form of data reduction or penalization is therefore necessary when modelling WAI. Another issue with developing WAI models is that there are substantial maturational effects on WAI through infancy that need to be controlled for. This can be achieved by either developing models for specific age groups (e.g., a model specifically for neonates), or by controlling for the effect of age by including interactions between age and WAI variables in a model, or by only using developmentally stable regions as predictor variables.Objective. The aim of this work was to investigate the diagnostic performance of WAI in infants by developing predictive models. Data reduction strategies such as selecting predictors based on prior research and principal component analysis were used to increase the likelihood that models would generalize to new samples. The effect of age was initially accounted for by developing age-specific models for neonates, 6-month infants, and 12-month infants (Chapters 2, 3 and 4, respectively). Longitudinal developmental effects on WAI through infancy were then investigated in Chapter 5, and this knowledge was used to develop a model controlling for the effect of age through infancy (6 to 18 months) (Chapter 6, Study 1). The neonate model was assessed for generalizability by applying the model to results from a new sample of infants (Chapter 6, Study 2)ii Methods. Tympanometry, distortion product otoacoustic emissions (DPOAEs) and ...

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“…Two of these studies, one conducted by Wake et al (2006) and Lyons, Kei, and the other by Driscoll (2004) shared the same cohort of school children as Driscoll et al (2001) and Cone et al (2010), respectively, and were subsequently excluded. The study conducted by Kei, Brazel, Crebbin, Richards, and Willeston (2007) was also excluded from further analysis due to small sample size (n = 50) and non-representative sample (participants were recruited from a single primary school in the Sunshine Coast, Queensland, Australia). As a result, three independent studies by Driscoll et al (2001), Cone et al (2010) and Keogh et al (2010) were included for further analysis in this review.…”

Section: Definition Of Degrees Of Hearing Lossmentioning

confidence: 99%

Evaluating auditory function in primary school children with learning difficulties in Australia

Choi

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Children who experience poor academic performance at school have been described as having learning difficulties (LD). These children are thought to show reduced performances in reading, written language and numeracy, and to be inactive and inefficient learners. Hearing is one of several factors thought to influence a child's learning at school with students spending at least 45% of their classroom activities that require listening and 45 to 75% of their time in the classroom comprehending their teachers' and classmates' speech. Hearing impairment can include loss of hearing sensitivity and/or impaired auditory processing (AP). While rates of peripheral hearing loss (PHL) in the Australian primary school-aged population is estimated to be between 3.4% and 12.8%, rates of impaired AP in this population are not available in Australia. Children with PHL and/or impaired AP often show behaviours similar to those reported in children with LD, suggesting that LD and hearing impairment could be related in primary school child populations. The present thesis aimed to investigate LD and hearing impairment in a schoolaged child population in the greater Brisbane region of Queensland, Australia. The thesis considered two main research questions: (1) Do children with LD have higher rates of impaired hearing and/or impaired AP compared with typically developing (TD) children?; and (2) What models might best explain any relationships between LD and hearing impairment? The first study chapter conducted a systematic review where the rate of PHL in the general primary school child population in Australia was considered. A search of five electronic databases yielded three studies that had quantitatively reported the PH results of screening and follow-up assessment of hearing in primary school children in Australia. The review concluded that the overall rate estimate of PHL in the primary school child population in Australia was between 3.4% and xii Financial Support

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High frequency distortion product otoacoustic emissions in children with and without middle ear dysfunction

Cited by 10 publications

References 26 publications

Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

Effect of chronic suppurative otitis media on distortion product otoacoustic emission input–output functions in conventional and ultra-high frequencies

Diagnosing conductive dysfunction in infants using wideband acoustic immittance: development and validation of predictive models

Evaluating auditory function in primary school children with learning difficulties in Australia

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