High‐flow Oxygen Therapy for Treating Bronchiolitis in Infants

Gordon, Isaac; Khan, Ambreen Shafaat

doi:10.1111/acem.13681

Cited by 3 publications

(12 citation statements)

References 9 publications

(20 reference statements)

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“…Of these, 180 were kept for full-text review, and 63 unique studies were included in the review (Figure 1). Fifteen of 32 authors responded to our requests for more details on outcomes or population, which improved data availability for 10 studies . Most included studies were conducted in the US (55 [87%]), 5 were from Australia, and 3 were from Canada .…”

Section: Resultsmentioning

confidence: 77%

“… Fifteen of 32 authors responded to our requests for more details on outcomes or population, which improved data availability for 10 studies . Most included studies were conducted in the US (55 [87%]), 5 were from Australia, and 3 were from Canada . All studies were published within the last 10 years (2013 to 2021).…”

Section: Resultsmentioning

confidence: 99%

“…All studies were published within the last 10 years (2013 to 2021). Studies used mainly preintervention-postintervention (n = 39) and ITS (n = 21) designs; only 1 was an RCT, and 2 were cohort studies . The EPG intervention was used to help reduce opioid prescriptions in 21 studies; PDMP, in 19 studies; EMR-QC, in 11 studies; CPC, in 10 studies; and PT, in 2 studies .…”

Section: Resultsmentioning

confidence: 99%

“…Studies used mainly preintervention-postintervention (n = 39) and ITS (n = 21) designs; only 1 was an RCT, and 2 were cohort studies . The EPG intervention was used to help reduce opioid prescriptions in 21 studies; PDMP, in 19 studies; EMR-QC, in 11 studies; CPC, in 10 studies; and PT, in 2 studies . Fifty-two studies included a mix of pain problems, and 56 included both acute and chronic pain .…”

Section: Resultsmentioning

confidence: 99%

“…The EPG intervention was used to help reduce opioid prescriptions in 21 studies; PDMP, in 19 studies; EMR-QC, in 11 studies; CPC, in 10 studies; and PT, in 2 studies . Fifty-two studies included a mix of pain problems, and 56 included both acute and chronic pain . The opioid prescription rate was reported for 25 studies, the prescribed opioid quantity for 13 studies, and both for 25 studies (Table 1).…”

Section: Resultsmentioning

confidence: 99%

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Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department

et al. 2022

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Key Points Question Are interventions to reduce pain-related opioid prescribing for patients who are discharged from the emergency department associated with variation in opioid prescription rate and/or prescribed opioid quantity? Findings In this meta-analysis of 63 unique studies, 34 of 51 studies assessing prescribing rates (67%) reported a significant reduction after intervention implementation, and 17 of the 39 studies assessing prescribed opioid quantity (44%) reported a significant intervention-related reduction. There were no data on patient-centered outcomes such as pain relief. Meaning This analysis found that specific interventions may be associated with reducing the opioid prescription rate; however, novel interventions are needed to reduce the quantity of opioids per prescription by emergency department physicians while evaluating their associations with patient-centered outcomes.

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Section: Resultsmentioning

confidence: 77%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 3 more Smart Citations

Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department

et al. 2022

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The impact of an autonomous nurse‐led high‐flow nasal cannula oxygen protocol on clinical outcomes of infants with bronchiolitis

Elks

Young

Kearney

et al. 2022

Journal of Clinical Nursing

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Objective: To investigate the relationship of the implementation of a nurse-led highflow nasal cannula oxygen protocol on the clinical outcomes of infants with bronchiolitis in a regional paediatric unit.Background: Bronchiolitis is a common lower respiratory illness and is the leading cause for hospitalisation of infants globally. Standard care involves the provision of supportive measures. Historically, supplemental oxygen was provided by low-flow nasal cannula. High-flow nasal cannula oxygen has been increasingly adopted despite limited evidence of its efficacy. Methods:This study employed non-equivalent, post-implementation only design to explore clinical outcomes of infants with bronchiolitis admitted for high-flow nasal cannula oxygen therapy. The study compared infants in the 24 months before and after the initiation of a high-flow nasal cannula protocol. The primary clinical outcome was length of stay, secondary outcomes included time on high flow, weaning time, escalation of care and time outside of physiological parameters. Implementation strategy evaluation was measured by compliance with applying the protocol, reported as episodes of variance, and duration of variance. The StaRI checklist was selected as the most appropriate reporting guideline.Results: A total of 80 patients were admitted with bronchiolitis and received highflow nasal cannula oxygen therapy during a 48-month period; 37 patients were prior, and 43 after, the introduction of a nurse-led high-flow nasal cannula protocol. Length of stay was significantly reduced in the post-implementation group compared to the historical control group (83.8 vs. 61.3 h). Time on high flow and weaning time was decreased in the post-implementation group compared to the control group (33.5 vs. 26.7 h and 26 vs.12.25 h, respectively); however, these did not reach statistical significance. There was varied application of the HFNC protocol. Conclusions:The implementation of a nurse-led high-flow nasal cannula protocol was associated with a reduced length of stay.

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Effects of celecoxib on AQP-1, NF-κB and apoptosis in lung tissue of neonatal rats with hyperoxia-induced lung injury

Zhengfei Fan,

Yuan Shen

2023

Cell Mol Biol (Noisy-le-grand)

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High‐flow Oxygen Therapy for Treating Bronchiolitis in Infants

Cited by 3 publications

References 9 publications

Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department

Evaluation of Interventions to Reduce Opioid Prescribing for Patients Discharged From the Emergency Department

The impact of an autonomous nurse‐led high‐flow nasal cannula oxygen protocol on clinical outcomes of infants with bronchiolitis

Effects of celecoxib on AQP-1, NF-κB and apoptosis in lung tissue of neonatal rats with hyperoxia-induced lung injury

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