High flow nasal cannula oxygen therapy in the treatment of acute bronchiolitis in neonates

Barrezueta, Lorena Bermúdez; Carbonell, Nuria García; Montes, Jorge López; Zafra, R.; Reina, Purificación Marín; Herrmannova, Jana; Soriano, Javier Casero

doi:10.1016/j.anpede.2016.03.006

Cited by 5 publications

(9 citation statements)

References 39 publications

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“…In pediatrics, there is scarcity in the studies assessing the benefit of HFNC in mortality rate and PICU length of stay. Some of the studies showed that HFNC does not reduce PICU LOS when compared to the time before its use [8,9]. While others showed a significant reduction in PICU length of stay (LOS) [10,13].…”

Section: Discussionmentioning

confidence: 99%

“…The use of HFNC is effective in reducing the work of breathing and improving many physiological parameters. Many studies showed the benefit of HFNC in reducing heart rate, respiratory rate, and increasing oxygenation and saturation [8][9][10]43]. Most of the studies showed improvement after 60 to 90 minutes from starting the intervention [43,44].…”

Section: Discussionmentioning

confidence: 99%

“…Fifty-six neonates were involved in each arm of the study. The main finding was a significant reduction in the use of noninvasive ventilation (NIV) after the use of HFNC and 2 patients required intubation in the pre-HFNC era while none after its use [8]. Two retrospective observational studies showed that HFNC decreased the intubation rate in infants less than 24 months of age admitted with viral bronchiolitis [9,10].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pediatric High Flow Nasal Cannula Experience in a Tertiary Care Hospital in Saudi Arabia

Tareq¹,

Chahdah²,

Moath³

et al. 2020

AJP

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Pediatric High Flow Nasal Cannula Experience in a Tertiary Care Hospital in Saudi Arabia

Tareq¹,

Chahdah²,

Moath³

et al. 2020

AJP

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“…Las infecciones respiratorias agudas (IRA) pertenecen al grupo de enfermedades infecciosas más frecuentes en pediatría 1 . En Argentina, las IRA constituyen la tercera mayor causa de muerte en niños menores de 1 año 2 .…”

Section: Introductionunclassified

Utilización de la cánula nasal de alto flujo en niños con diagnóstico de bronquiolitis menores de dos años: estudio retrospectivo

Díaz¹

2020

RFEM

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Introducción. La cánula nasal de alto flujo (CNAF) podría funcionar como te rapia de rescate reduciendo las probabilidades de requerir internación en la Unidad de Cuidados Intensivos Pediátricos (UCIP), disminuyendo la necesidad de ventilación mecánica invasiva en pacientes con bronquiolitis. Materiales y métodos. Estudio retrospectivo en pacientes de 24 meses de edad o menos, con diagnóstico de bronquiolitis y falla de la oxigenoterapia conven cional, con posterior colocación de CNAF en sala pediátrica. El objetivo fue describir los registros de frecuencia respiratoria (FR), frecuencia cardíaca (FC), mecánica respiratoria (MR) y saturometría de pulso al inicio de la terapia, a la hora, a las 4, 24 y 48 horas y la falla del tratamiento interpretada como el pase del paciente a la UCIP. Resultados. Se incluyeron 27 pacientes cuyos resultados mostraron una dismi nución progresiva en el tiempo posterior a la colocación de la CNAF de FC, FR y MR. Un 26% (n=7) ingresaron a UCIP. Conclusión. La CNAF podría ser una alternativa efectiva y segura como trata miento en nuestra serie de menores de dos años con diagnóstico de bronquio litis, y podría disminuir el ingreso a UCIP.

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“…Bronchiolitis is a disease that, even though has low mortality, requires many resources (3, 4). However, there are still questions regarding the most appropriate management.…”

mentioning

confidence: 99%

High-Flow Oxygen and Other Noninvasive Respiratory Support Therapies in Bronchiolitis: Systematic Review and Network Meta-Analyses

Moreno

Guerra

Medina

et al. 2022

Pediatric Critical Care Medicine

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We present a systematic review on the effectiveness of noninvasive respiratory support techniques in bronchiolitis.DATA SOURCES: Systematic review with pairwise meta-analyses of all studies and network meta-analyses of the clinical trials. STUDY SELECTION:Patients below 24 months old with bronchiolitis who require noninvasive respiratory support were included in randomized controlled trials (RCTs), non-RCT, and cohort studies in which high-flow nasal cannula (HFNC) was compared with conventional low-flow oxygen therapy (LFOT) and/or noninvasive ventilation (NIV). DATA EXTRACTION: Emergency wards and hospitalized patients with bronchiolitis.DATA SYNTHESIS: A total of 3,367 patients were analyzed in 14 RCTs and 8,385 patients in 14 non-RCTs studies. Only in nonexperimental studies, HFNC is associated with a lower risk of invasive mechanical ventilation (MV) than NIV (odds ratio, 0.49; 95% CI, 0.42-0.58), with no differences in experimental studies. There were no differences between HFNC and NIV in other outcomes. HFNC is more effective than LFOT in reducing oxygen days and treatment failure. In the network meta-analyses of clinical trials, NIV was the most effective intervention to avoid invasive MV (surface under the cumulative ranking curve [SUCRA], 57.03%) and to reduce days under oxygen therapy (SUCRA, 79.42%), although crossover effect estimates between interventions showed no significant differences. The included studies show methodological heterogeneity, but it is only statistically significant for the reduction of days of oxygen therapy and length of hospital stay. CONCLUSIONS:Experimental evidence does not suggest that high-flow oxygen therapy has advantages over LFOT as initial treatment nor over NIV as a rescue treatment.

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High flow nasal cannula oxygen therapy in the treatment of acute bronchiolitis in neonates

Cited by 5 publications

References 39 publications

Pediatric High Flow Nasal Cannula Experience in a Tertiary Care Hospital in Saudi Arabia

Pediatric High Flow Nasal Cannula Experience in a Tertiary Care Hospital in Saudi Arabia

Utilización de la cánula nasal de alto flujo en niños con diagnóstico de bronquiolitis menores de dos años: estudio retrospectivo

High-Flow Oxygen and Other Noninvasive Respiratory Support Therapies in Bronchiolitis: Systematic Review and Network Meta-Analyses

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