High Field MR Imaging of Cerebral Venous Thrombosis

Macchi, Paul J.; Grossman, Robert I.; Gomori, John M.; Goldberg, Herbert I.; Zimmerman, Robert A.; Bilaniuk, Larissa T.

doi:10.1097/00004728-198601000-00002

Cited by 175 publications

(52 citation statements)

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“…The shape of signal-intensity changes was very similar to that of the "cord" sign, a rare CT indicator of CVT only reported in 2 cases with MR imaging on T1-weighted images. 13,19 Of note, MSE was detected in the 4 patients examined within 5 days after clinical onset when there was no hyperintense vessels on T1-weighted images. In addition, although a moderate-to-intense hyposignal of the thrombosed vein was also detected on FLAIR images in 6 patients within the first week after clinical onset (not previously detected), the detection of MSE was found helpful to discern these subtle vascular signal-intensity changes.…”

Section: Discussionmentioning

confidence: 97%

MR Imaging Features of Isolated Cortical Vein Thrombosis: Diagnosis and Follow-Up

Boukobza¹,

Crassard²,

Bousser³

et al. 2008

AJNR Am J Neuroradiol

136

118

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Section: Discussionmentioning

confidence: 97%

MR Imaging Features of Isolated Cortical Vein Thrombosis: Diagnosis and Follow-Up

Boukobza¹,

Crassard²,

Bousser³

et al. 2008

AJNR Am J Neuroradiol

136

118

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“…In children, radiologic recanalization as early as 2 weeks after the onset of clinical symptoms has been reported. 669 Predictors of poor outcome include presentation with venous infarcts or seizures 383 and, for death, presentation with coma. 668 In the Canadian Pediatric Ischemic Stroke Registry, nearly 25% of children showed an increased severity of neurologic defi cits developing over time, reinforcing the need for long-term follow-up.…”

Section: Csvt In Childrenmentioning

confidence: 99%

Antithrombotic Therapy in Neonates and Children

Monagle

Chan

Goldenberg

et al. 2012

Chest

1,241

559

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“…[13][14][15][16][17][18] Both occur during blood stasis; thus, they contain a large mass of red blood cells and appear as red thrombi. 7 The hemoglobin products of red blood cells have a dramatic effect on water magnetic relaxation and are therefore the main determinants of the MRI appearance.…”

mentioning

confidence: 99%

MRI of Atherothrombosis Associated With Plaque Rupture

Viereck¹,

Ruberg²,

Qiao³

et al. 2005

ATVB

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Objective-MRI would be a valuable noninvasive diagnostic tool to study plaque-associated thrombi. We defined the imaging characteristics of these thrombi, composed primarily of platelets and fibrin, and distinguished them clearly from the vessel lumen and underlying atherosclerotic plaque in an animal model of plaque rupture. Methods and Results-After triggering plaque rupture in New Zealand White male rabbits, segments of infrarenal aorta containing either red or white thrombi were fixed in formalin. Compared with postmortem red cell-rich thrombi, atherothrombi yielded complex magnetic resonance images with intermediate signal intensity in standard T1-and T2-weighted imaging sequences and were often difficult to distinguish from the aortic wall. Diffusion-weighted imaging sequences revealed restricted diffusion of the atherothrombus relative to the vessel wall and provided excellent contrast. The apparent diffusion coefficient of the thrombus is 1.0ϫ10 Ϫ3 mm 2 /s, compared with 1.5ϫ10 Ϫ3 mm 2 /s in tissue. Similar results were obtained using purified aggregated platelets. Conclusions-We present the first detailed description of the MRI appearance of plaque rupture-associated thrombosis in histologically validated platelet-rich thrombi. Diffusion-weighted imaging provided the best distinction between thrombus and vessel wall and has potential application for the noninvasive in vivo detection of atherothrombosis.

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High Field MR Imaging of Cerebral Venous Thrombosis

Cited by 175 publications

References 0 publications

MR Imaging Features of Isolated Cortical Vein Thrombosis: Diagnosis and Follow-Up

MR Imaging Features of Isolated Cortical Vein Thrombosis: Diagnosis and Follow-Up

Antithrombotic Therapy in Neonates and Children

MRI of Atherothrombosis Associated With Plaque Rupture

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