High early mortality rate from acute pancreatitis in Scotland, 1984–1995

McKay, Colin; Evans, Susan; Sinclair, Martin; Carter, C R; Imrie, C. W.

doi:10.1046/j.1365-2168.1999.01246.x

Cited by 259 publications

(156 citation statements)

References 19 publications

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“…Since its development, several other scoring systems, such as the Glasgow criteria [23][24][25] , APACHE-Ⅱ score [7,26] , BISAP [11] , and CTSI [8] , have been developed. These…”

Section: Discussionmentioning

confidence: 99%

Comparison of scoring systems in predicting severity of acute pancreatitis

Chung

Kim

2013

Pancreatology

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“…Since its development, several other scoring systems, such as the Glasgow criteria [23][24][25] , APACHE-Ⅱ score [7,26] , BISAP [11] , and CTSI [8] , have been developed. These…”

Section: Discussionmentioning

confidence: 99%

Comparison of scoring systems in predicting severity of acute pancreatitis

Chung

Kim

2013

Pancreatology

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“…Early mortality (up to 60% of all deaths) [11] results from an overactive systemic inflammatory response syndrome (SIRS) over the first week, while the remainder deaths are secondary to local complications, infection and sepsis after the second week. Characterization of these patterns of severity progression, have not yet been translated into effective prediction of severe disease upon patient admission based on traditional parameters [12][13][14].…”

Section: Acute Pancreatitismentioning

confidence: 99%

Intra-abdominal hypertension and abdominal compartment syndrome in acute pancreatitis, hepato-pancreato-biliary operations and liver transplantation

Bressan

Ball

2017

Anaesthesiol Intensive Ther

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Intra-abdominal hypertension, even preceding the onset of abdominal compartment syndrome, is still recognized as an adverse prognostic factor. Unfortunately, most of the current supporting evidence within the critical care environment remains observational in nature. In acute pancreatitis, an active role for intra-abdominal hypertension early in the disease process follows a strong intuitive basis, and it is corroborated by preliminary evidence from animal models. Additional studies are needed to better characterize the optimal fluid resuscitation strategy, as well as the importance of intra-abdominal hypertension as an early therapeutic target. All critically ill patients with acute pancreatitis should be considered for routine intra-abdominal pressure monitoring. The prevalence and clinical relevance of intra-abdominal hypertension after elective major abdominal operations are underestimated in the literature. Hepato-pancreato-biliary surgery and liver transplantation represent high-risk surgical subspecialties, and routine intra-abdominal hypertension risk assessment to indicate postoperative intra-abdominal pressure monitoring can be recommended. Conservative management of intra-abdominal hypertension should be promptly initiated upon diagnosis. Although abdominal catheter drainage and decompressive laparotomy may be required in refractory cases based on expert clinical judgment, precise indications and timing are still unclear. Implementation of institutional protocols based on the Abdominal Compartment Society reference standards is crucial to optimize both clinical management and research in this evolving area.

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“…1 About 80% of the attacks are mild, 20% are severe and they are commonly accompanied by necrosis of the pancreas and or organ failure. 2 Gall stones and chronic ethanol abuse account for 70% of cases of acute pancreatitis. 3 Pathologically there are two types of pancreatitis, interstitial and necrotizing.…”

Section: Introductionmentioning

confidence: 99%

“…9,10 About one fourth to one third of the acute severe pancreatitis patients die from the disease, for a total mortality of 2-10%. 11 About one fourth of the deaths in Scotland occur within 24 hrs of admission. 12 After the second week of illness patients succumb to pancreatic infection associated with multi-organ failure.…”

Section: Introductionmentioning

confidence: 99%