High-dose rate brachytherapy as monotherapy in prostate cancer: A systematic review of its safety and efficacy

Sánchez-Gómez, Luís María; Polo-deSantos, M.; Rodríguez-Melcón, J.I.; Angulo, Javier; Luengo-Matos, Setefilla

doi:10.1016/j.acuroe.2016.12.001

Cited by 2 publications

(3 citation statements)

References 39 publications

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“…LDR-BT is a curative and cost-effective treatment strategy for localised prostate cancer alongside surgery and radiation therapy. 9 Owing to the good treatment outcomes, the patient's age, QOL and preferences are major concerns when deciding on the primary treatment of prostate cancer. Brachytherapy was reported to be similar to, but less expensive than, intensity-modulated radiation therapy and radical prostatectomy with regard to quality-adjusted life expectancy and average lifetime cost.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of tadalafil against lower urinary tract symptoms after low-dose-rate brachytherapy in prostate cancer patients

Saito

Minagawa

Ogawa

et al. 2018

Journal of Clinical Urology

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This study was performed to evaluate the effects of addition of tadalafil to tamsulosin in the treatment of brachytherapy patients with lower urinary tract symptoms (LUTS). Methods: Localized prostate cancer patients who developed LUTS after low-dose-rate brachytherapy (LDR-BT) were first treated with alpha-1 blockers (tamsulosin, 0.2 mg per day). Those still suffering from LUTS were additionally treated with phosphodiesterase type 5 inhibitor (tadalafil, 5 mg/day). LUTS was evaluated by the International Prostate Symptom Score (IPSS), IPSS Quality of Life (QOL) score, Overactive Bladder Symptom Score (OABSS), and the International Index of Erectile Function 5 (IIEF5) score before brachytherapy, before treatment with tadalafil, and after three months of treatment with tadalafil. Results: Twenty-three patients were enrolled in the study. Each subscore of the IPSS (storage symptom, voiding symptom, and postvoiding symptom) and the QOL score improved, but OABSS and IIEF5 did not show significant recovery after addition of tadalafil treatment. When patient characteristics and each question score were surveyed, time from seed implantation until treatment with tadalafil showed the strongest correlation with recovery. Conclusions: Addition of tadalafil to tamsulosin treatment was effective against LUTS in localised prostate cancer patients after brachytherapy.

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Section: Discussionmentioning

confidence: 99%

Efficacy of tadalafil against lower urinary tract symptoms after low-dose-rate brachytherapy in prostate cancer patients

Saito

Minagawa

Ogawa

et al. 2018

Journal of Clinical Urology

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“…The search process was performed on 23 March 2021. Our search string contained “brachytherapy” and all its related keywords selected from Medical Subject Headings (MeSH) and other similar research projects 19–23 . As a result, a list of keywords related to brachytherapy was created.…”

Section: Methodsmentioning

confidence: 99%

“…Our search string contained "brachytherapy" and all its related keywords selected from Medical Subject Headings (MeSH) and other similar research projects. [19][20][21][22][23] As a result, a list of keywords related to brachytherapy was created. The search strategy that was used to retrieve our data was: TS = ("brachytherapy" OR "curietherapy" OR "radioisotope plaque therapy" OR "plaque radiotherapy" OR "surface radiotherapy" OR "internal radiotherapy" OR "internal radiation therapy" OR "intracavity radiotherapy" OR "interstitial radiotherapy" OR "intraluminal radiotherapy" OR "intravascular radiotherapy" OR "implant radiotherapy") Indexes = SCI-EXPANDED, SSCI, A&HCI, CPCI-S, CPCI-SSH, BKCI- Retrieved documents were limited to publications before 2021 (timespan 1900-2020).…”

Section: Data Source and Inclusion Criteriamentioning

confidence: 99%

Knowledge domain and emerging trends in brachytherapy: A scientometric analysis

Ghazbani

Abdolahi

Mansourzadeh

et al. 2022

Precision Radiation Oncology

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Objective: Assessing the current scientific situation helps to recognize the gaps and strengths of brachytherapy research projects. This research project was conducted to assess the knowledge domain and emerging trends in brachytherapy through a scientometric perspective. Methods:For the present research, the Web of Science database was considered as the data source. Integrated data was transferred to Bibliometrix R Package V3.1. In this study, the scientometric approach was performed by CiteSpace 5.8.R3 to draw the trends and signify issues in the research area. Eventually, scientometric indicators were evaluated at the level of authors, documents, journals, organizations, and countries.Results: A total of 31,362 documents from 64,740 Independent researchers were retrieved. The United States, Germany, and Canada were the most active countries in brachytherapy-related research projects. In the present study, Luc Beaulieu, Christine Kirisits, and Ronald Nath were identified as the most influential authors. Eventually, keywords clusters were constructed by using the method of co-citation analysis. In this case, the main clusters were cervical cancer and prostate cancer. Conclusion:Assessing the scientific trends in brachytherapy indicated that new insights have been gained into this cancer treatment technique. In this case, development of computer applications and artificial intelligence alongside deep learning utilization provides new horizons for oncology and radiotherapy researchers.

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High-dose rate brachytherapy as monotherapy in prostate cancer: A systematic review of its safety and efficacy

Cited by 2 publications

References 39 publications

Efficacy of tadalafil against lower urinary tract symptoms after low-dose-rate brachytherapy in prostate cancer patients

Efficacy of tadalafil against lower urinary tract symptoms after low-dose-rate brachytherapy in prostate cancer patients

Knowledge domain and emerging trends in brachytherapy: A scientometric analysis

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