High dose pyridoxine for the treatment of tardive dyskinesia: clinical case and review of literature

Umar, Murtala M; Isa, Aliyu A.; Abba, Asmaul H.

doi:10.1177/2045125315616738

Cited by 2 publications

(1 citation statement)

References 27 publications

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“…It has been now the common practice to withdraw ongoing antipsychotic and use clozapine for treatment of TD [6]. Other than clozapine, highly selective vesicular monoamine transporter 2 inhibitor, tetrabenazine, valbenazine, high dose pyridoxine, bilateral Deep Brain Stimulation (DBS) are recommended options in TD treatment [35][36][37][38][39]. In this study clozapine given to a TD patient and was responded at 50mg/day which matches other evidences [6].…”

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confidence: 70%

Profile of Clozapine Therapy: a Cross Sectional Piloting in a Tertiary Care Setting of Bangladesh

MS¹

2017

J Psychiatry Psychiatric Disord

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Clozapine is a very important atypical antipsychotic indicated for one to two third patients of resistant psychotic symptoms. It is also indicated in Treatment Resistant Bipolar Disorder (TRBD), Tardive Dyskinesia (TD) and few other indications. Most common side effects of clozapine are hypersalivation, sedation, constipation, hypertension, hypotension, fever, seizure, tachycardia, nocturnal enuresis and agranulocytosis. The study aimed to look into the patients getting clozapine in respect of demography, disease and side effects profile. This cross sectional study was conducted among 21 hospitalised patients those getting clozapine. The data were collected with semi structured questionnaire and preformed checklist through face to face interview, physical examination and available laboratory investigations. Majority of the patients were male and Resistant Schizophrenia was most common diagnosis. The

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