Abstract:Background The same dosing schedule, 1000 SQ-U times three, with
one-month intervals, have been evaluated in most trials of
intralymphatic immunotherapy (ILIT) for the treatment of allergic
rhinitis (AR). The present studies evaluated if a dose escalation in
ILIT can enhance the clinical and immunological effects, without
compromising safety. Methods Two randomized double-blind
placebo-controlled trials of ILIT for grass pollen induced AR were
performed. The first included 29 patients that had recently ended 3… Show more
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