High-dose IV immunoglobulin for peripheral neuropathy associated with Sjögren's syndrome

Abstract

syndrome High-dose IV immunoglobulin for peripheral neuropathy associated with Sjögren's This information is current as of

Motor Dominant Neuropathy in Sjoegren's Syndrome: Report of Two Cases.

“…With regard to therapy, Pascual et al first tried i.v. immunoglobulin as a treatment for peripheral sensory neuropathy in SS, and obtained the beneficial effects (10). Our findings indicate that i.v.…”

Intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: Present status and practical therapeutic guidelines

“…Intravenous immunoglobulin has been reported to be helpful in rare, isolated case reports of patients with acute dysautonomic neuropathy, 76 paraneoplastic sensory neuronopathy with anti-Hu antibodies 49 (in our experience, these patients do not respond), in a patient with axonal neuropathy associated with Sjögren's syndrome 112 (our experience does not confirm such benefit), rare cases of vasculitis, 82 in idiopathic lumbosacral plexopathy, 133 and in a patient with polyneuropathy associated with osteosclerotic myeloma.…”

Upper Motor Neuron Syndrome Associated with Subclinical Sjoegren's Syndrome

“…We Di f f u s e p u n c t a t e s i a l e c t a s i s i s s e e n i n t h e l e f t p a r o t i d g l a n (Fig. 3) (9,10). In contrast to methylprednisolone pulse therapy and plasma exchange, IVIG has multiple mechanisms of action, including suppression of the opsonin effect, neutralization of cytokines, and reduced production of antibodies (11) …”