2013
DOI: 10.1016/j.ijrobp.2013.08.040
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High-Dose and Extended-Field Intensity Modulated Radiation Therapy for Early-Stage NK/T-Cell Lymphoma of Waldeyer's Ring: Dosimetric Analysis and Clinical Outcome

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Cited by 52 publications
(55 citation statements)
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References 33 publications
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“…4,5,9,10,[15][16][17]25 Other studies reported similar improvement after upfront RT over CT alone. 1,[18][19][20] However, this advantage needs to be validated in a multi-institution setting.…”
Section: Introductionmentioning
confidence: 84%
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“…4,5,9,10,[15][16][17]25 Other studies reported similar improvement after upfront RT over CT alone. 1,[18][19][20] However, this advantage needs to be validated in a multi-institution setting.…”
Section: Introductionmentioning
confidence: 84%
“…RT included extended field or extended involved field encompassing the primary tumor and adjacent regions at a radical dose of 50 Gy, with a 6-to 10-Gy boost to residual disease. 15,16 Median dose was 50 Gy (range, 36-74 Gy; dose per fraction, 1.8-2 Gy). Of patients receiving CT, 826 (81.0%) received cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) or CHOP-like regimens (old regimens), whereas 194 (19.0%) received L-asparaginase-based (n 5 126) or gemcitabine-based (n 5 68) regimens (new regimens), such as dexamethasone, methotrexate, ifosfamide, L-asparaginase, and etoposide; gemcitabine, cisplatin, and dexamethasone; or dexamethasone, ifosfamide, methotrexate, and gemcitabine.…”
Section: Treatmentmentioning
confidence: 99%
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“…Few prospectively designed, randomized and controlled clinical trials have been conducted to explore the survival benefit of RT for early-stage ENKTL patients and current evidence mainly relies on retrospective studies and series case reports with small samples. Additionally, most of them were conducted in Asian countries [6,9,[12][13][14][16][17][18][19][20]. In view of above, we conducted a population-based analysis of patients with early-stage ENKTL from the Surveillance, Epidemiology, and End Results (SEER) database to evaluate the survival benefit associated with RT and investigate the prognostic factors for early-stage ENKTL patients.…”
Section: Introductionmentioning
confidence: 99%