Current Opinion in Lipidology volume 25, issue 3, P194-199 2014 DOI: 10.1097/mol.0000000000000074 View full text
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Ernst J. Schaefer, Pimjai Anthanont, Bela F. Asztalos

Abstract: Purpose of review Our purpose was to examine recent advances in our knowledge of high density lipoprotein (HDL) metabolism, composition, function, and coronary heart disease (CHD), as well as marked HDL deficiency states due to mutations at the apolipoprotein (apo) A-I, ATP binding cassette transfer protein A1 (ABCA1), and lecithin cholesterol acyltransferase (LCAT) gene loci. Recent findings It has been documented that apoA-I, myeloperoxidase (MPO), and paraoxonase 1 (PON1) form a complex in HDL that is c…

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