2019
DOI: 10.1016/j.anaerobe.2019.04.004
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High delayed mortality after the first episode of Clostridium difficile infection

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Cited by 5 publications
(5 citation statements)
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“…Over the last decade, there has been a marked increase in the incidence and severity of CDI, with relapsing episodes now occurring at a higher frequency, especially in the elderly. Notably, recurrent CDI is associated with a significantly higher risk of death within six months after initial CDI treatment completion, compared with CDI patients who do not develop a recurrence [18,19].…”
Section: Discussionmentioning
confidence: 99%
“…Over the last decade, there has been a marked increase in the incidence and severity of CDI, with relapsing episodes now occurring at a higher frequency, especially in the elderly. Notably, recurrent CDI is associated with a significantly higher risk of death within six months after initial CDI treatment completion, compared with CDI patients who do not develop a recurrence [18,19].…”
Section: Discussionmentioning
confidence: 99%
“…Our results are similar to those of other authors. In a multi-center study by Cózar et al [ 5 ], mortality among patients with three aggravating factors, such as heart failure, kidney failure, cancer, diabetes was twice as high as in patients with two factors. Particularly noteworthy are cardiovascular diseases, the presence of which increases the risk of death [ 25 ], especially the presence of ischemic heart disease [ 33 ] or heart failure [ 38 ], in which case mortality increased to approx.…”
Section: Discussionmentioning
confidence: 99%
“…CDI is a severe disease with a high mortality rate [ 5 7 ]. Its course is highly variable, from mildly symptomatic cases, requiring only discontinuation of the current antibiotic therapy, to complicated forms, including septic shock.…”
Section: Introductionmentioning
confidence: 99%
“…Our study shows that this late mortality is even higher in cancer patients. CDI is a devastating illness, causing long hospitalizations, immobilization, long-term dysbiosis, and potential delay in scheduled chemotherapy cycles (Cózar et al, 2019) (Dutta and Lim, 2020). All these features may explain the higher late mortality in this group.…”
Section: Discussionmentioning
confidence: 99%