High-Degree Concentration Organic Solvent Forward Osmosis for Pharmaceutical Pre-Concentration
Ryoichi Takada,
Ryosuke Takagi,
Hideto Matsuyama
Abstract:Over half of the pharmaceutical industry’s capital investments are related to the purification of active pharmaceutical ingredients (APIs). Thus, a cost-effective purification process with a highly concentrated solution is urgently required. In addition, the purification process should be nonthermal because most APIs and their intermediates are temperature-sensitive. This study investigated a high-degree concentration organic solvent forward osmosis (OSFO) membrane process. A polyketone-based thin-film composi… Show more
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