High-definition transcranial direct-current stimulation of the right M1 further facilitates left M1 excitability during crossed facilitation

Abstract

Cabibel et al. (J Neurophysiol 119: 1266-1272, 2018) report non-polarity-specific effects of high-definition direct current stimulation (HD-tDCS) on crossed facilitation (CF), demonstrated by complex excitatory and inhibitory interhemispheric interactions coupled with HD-tDCS. Choosing a variety of stimulation and muscle contraction parameters and having all participants undergo anodal, cathodal, and sham stimulation may increase the current understanding of HD-tDCS on CF. Furthermore, complementary metrics like the ipsilateral silent period may provide more clarity regarding the polarity-specific enhancement of HD-tDCS on CF.