High costs, low quality of life, reduced survival, and room for improving treatment: an analysis of burden and unmet needs in glioma
Johannes Pöhlmann,
Michael Weller,
Andrea Marcellusi
et al.
Abstract:Gliomas are a group of heterogeneous tumors that account for substantial morbidity, mortality, and costs to patients and healthcare systems globally. Survival varies considerably by grade, histology, biomarkers, and genetic alterations such as IDH mutations and MGMT promoter methylation, and treatment, but is poor for some grades and histologies, with many patients with glioblastoma surviving less than a year from diagnosis. The present review provides an introduction to glioma, including its classification, e… Show more
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