High correlation of specific IgE sensitization between birch pollen, soy and apple allergens indicates pollen-food allergy syndrome among birch pollen allergic patients in northern China

Hao, Guodong; Zheng, Yiwu; Wang, Zhixiang; Kong, Xing-ai; Song, Zhi-jing; Lai, Xuxin; Spangfort, Michael D.

doi:10.1631/jzus.b1500279

Cited by 28 publications

(30 citation statements)

References 25 publications

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“…In addition, the importance of cat and dog sensitizations was underlined by the molecular studies identifying especially Fel d 1 and to a lower extent of Can f 1 as important allergens (36). Another interesting finding was that birch pollen allergy as confirmed by IgE reactivity to the major birch pollen allergen, Bet v 1 was found in patients from Beijing and Northern China (60). Bet v 1 patients also suffered from oral allergy syndrome due to cross-reactivity with Bet v 1-related PR10 allergens from plant food (60).…”

Section: Information Regarding Molecular Sensitization Profiles In China Through First Studies Performed With Molecular Diagnosticsmentioning

confidence: 98%

The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy

et al. 2021

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Approximately 30% of the world population suffers from immunoglobulin-E (IgE)-mediated allergy. IgE-mediated allergy affects the respiratory tract, the skin and the gastrointestinal tract and may lead to life-threatening acute systemic manifestations such as anaphylactic shock. The symptoms of allergy are mediated by IgE-recognition of causative allergen molecules from different allergen sources. Today, molecular allergy diagnosis allows determining the disease-causing allergens to develop allergen-specific concepts for prevention and treatment of allergy. Allergen-specific preventive and therapeutic strategies include allergen avoidance, vaccination, and tolerance induction. The implementation of these preventive and therapeutic strategies requires a detailed knowledge of the relevant allergen molecules affecting a given population. China is the world´s most populous country with around 1.4 billion inhabitants and an estimated number of more than 400 million allergic patients. Research in allergy in China has dramatically increased in the last decade. We summarize in this review article what is known about the dominating allergen sources and allergen molecules in China and what further investigations could be performed to draw a molecular map of IgE sensitization for China as a basis for the implementation of systematic and rational allergen-specific preventive and therapeutic strategies to combat allergic diseases in this country.

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Section: Information Regarding Molecular Sensitization Profiles In China Through First Studies Performed With Molecular Diagnosticsmentioning

confidence: 98%

The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy

et al. 2021

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“…Birch is the most important aero-allergenic tree in Europe, its pollen causing allergies in more than 100 million people and being the most frequent triggers of respiratory diseases: seasonal hay fever, asthma, and cross-reactive food allergy [104][105][106][107]. During certain meteorological conditions, birch pollen is transported over long distances, e.g., from Poland and Germany to Denmark [108].…”

Section: Aero-allergenic Treementioning

confidence: 99%

Potential of Birch (Betula pendula Roth and B. pubescens Ehrh.) for Forestry and Forest-Based Industry Sector within the Changing Climatic and Socio-Economic Context of Western Europe

Dubois

Verkasalo

Claessens

2020

Forests

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Five commercial tree species comprise nearly 80% of the forest standing stock volume in Western Europe. Nowadays, there is a strong need to consider a wider diversity of tree species, as evidenced by the impact of climate change and the forest health crises over the past decades. In this context, this study focuses on the potential of birch (Betula pendula Roth and Betula pubescens Ehrh.), a neglected indigenous species, for forestry and the forest-based industry sector. We have therefore compiled, analyzed, and discussed literature regarding the strengths and weaknesses of the species and the opportunities and threats of its use for this purpose. Among the strengths, birch tolerates various climates and sites, and high genetic variability promotes its adaptability. Birch improves forest resilience by colonizing forest gaps and quickly increasing soil functioning and biodiversity. Birch is also remarkably resistant to game overpopulation-associated damage. Large-sized logs are produced within relatively short periods with proper silvicultural treatment, and the wood characteristics allow versatile and valuable uses, as shown in Northern Europe. However, its weaknesses include high sensitivity to crown competition and to wood rot as challenges for silviculture. Among the opportunities, birch is well-suited to the global changes with its adaptability to climate change and its possible integration in diverse productive mixed tree stands. In the context of societal evolutions and customer perceptions, birch wood could play an increasing role in the building and furniture sectors, and among non-wood forest products. In Western Europe, the main obstacle to birch development is the lack of information on the wood uses and, consequently, the lack of interest among forest managers and wood processing professionals, which have led to a poor quality of the resource and to insufficient demand for its wood. Moreover, its fast height growth can affect the vitality of other species in mixed stands. Our analysis highlighted the potential of birch in the Western European forestry considering societal, ecological, and economic purposes in a changing climatic and socio-economic context and the need to (i) develop opportunities for industrial uses of birch wood, (ii) inform forest owners, managers, and industrial professionals about the potential value of birch, and (iii) define silvicultural guidelines.

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“…They were also observed in people with atopic diseases and those allergic to cow's milk [12]. An increase in allergic symptoms occurring after eating soy is also noted in people who are allergic to birch, especially during the pollination period [13][14][15].…”

Section: Introductionmentioning

confidence: 84%

Soy Preparations Are Potentially Dangerous Factors in the Course of a Food Allergy

Jędrusek‐Golińska

Piasecka‐Kwiatkowska

Zielińska

et al. 2019

Foods

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The special properties of soy preparations make them common additives for food production and can be dangerous for sensitive individuals. Our aim was to check consumers’ awareness of potential risks of soy preparations added to numerous food products, depending on respondents’ education, and to evaluate immunoreactive properties of chosen soy preparations. A personal questionnaire was used. Respondents (n = 251) were aged 23–28 years old, lived in Poland, and were graduates or students in their last year of food technology, medicine, and university of technology. The slot blot and Western blotting methods were used to mark immunoreactivity of soy preparations. It was shown that most respondents often or usually read labels of food products they buy. The surveyed indicated protein is the allergenic component in soy. Almost half of them were of the opinion that hydrolysis removes the allergenic properties of soy. Most of the medical students surveyed thought that people allergic to soy may consume products that contain soy preparations. The analytical results indicated that soy preparation contained protein fractions that were immunoreactive with sera of allergenic patients. It was proven that preparations, even hydrolysates, contain immunoreactive proteins that may be the source of hidden allergens, even though they are not recognized as dangerous by well-educated respondents.

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High correlation of specific IgE sensitization between birch pollen, soy and apple allergens indicates pollen-food allergy syndrome among birch pollen allergic patients in northern China

Cited by 28 publications

References 25 publications

The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy

The Molecular Allergen Recognition Profile in China as Basis for Allergen-Specific Immunotherapy

Potential of Birch (Betula pendula Roth and B. pubescens Ehrh.) for Forestry and Forest-Based Industry Sector within the Changing Climatic and Socio-Economic Context of Western Europe

Soy Preparations Are Potentially Dangerous Factors in the Course of a Food Allergy

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