High Body Mass Index and Posttransplant Weight Gain Are Not Risk Factors for Kidney Graft and Patient Outcome

Marcén, R.; Fernandez, Armida; Pascual, Julio; Teruel, J.L.; Villafruela, J.J.; Rodriguez, N.; Martins, Judith; Burgos, Francisco; Ortuño, J

doi:10.1016/j.transproceed.2007.07.072

Cited by 42 publications

(24 citation statements)

References 9 publications

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“…6 Obesity is a well-known risk factor for morbidity and mortality in the general population; however, being overweight or obese is associated with increased survival among dialysis patients. 4,10 The impact of weight gain on maintenance or loss of graft function graft function are controversial. In RT recipients.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Nutritional Status in Renal Transplant Recipients in Accordance with Changes in Graft Function

Tutal

Sezer

Uyar

et al. 2013

Transplantation Proceedings

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Section: Discussionmentioning

confidence: 99%

Evaluation of Nutritional Status in Renal Transplant Recipients in Accordance with Changes in Graft Function

Tutal

Sezer

Uyar

et al. 2013

Transplantation Proceedings

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“…[18] Several other studies, however, did not find any association between pre-transplant BMI and mortality. [19, 21, 22] Chang et al . reported that obesity per se was not associated with poorer kidney transplant outcomes, although it was associated with factors that led to poorer graft and patient survival.…”

Section: Discussionmentioning

confidence: 99%

Higher recipient body mass index is associated with post-transplant delayed kidney graft function

Molnar

Kövesdy

Mucsi

et al. 2011

Kidney International

126

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Delayed graft function (DGF) complicates kidney allograft outcomes in the immediate post-transplantation period. We hypothesized that in hemodialysis patients, high pre-transplant body mass index (BMI) is associated with higher risk of DGF. Linking 5-year hemodialysis patient data of a large dialysis organization to the Scientific Registry of Transplant Recipients, we identified 11,836 hemodialysis patients who underwent kidney transplantation during 7/2001-6/2007. We conducted multivariate logistic regression analyses to assess the association between pre-transplant BMI and post-transplant DGF. Patients were 49±14 (mean±SD) years old, had a BMI of 26.8±6.0 kg/m2, and included 38% women, 27% Blacks and 26% diabetics. After adjusting for relevant covariates, pre-transplant BMI remained an independent predictor of DGF. One SD increase in pre-transplant BMI was associated with a 35% higher risk of DGF (OR=1.35; 95% confidence interval [CI]: 1.27-1.44). Compared to patients with pre-transplant BMI of 22-24.99 kg/m2, patient with overweight (BMI 25-29.99 kg/m2), mild obesity (BMI 30-34.99 kg/m2) and moderate to severe obesity (BMI>=35 kg/m2) had 30%, 42% and 118% higher risks of DGF, respectively (p<0.05). Similar associations were observed in all patients subgroups. Pre-transplant overweight/obesity is associated with incrementally higher risk of DGF.

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“…[4][5][6][7][8] Analyses of the effect of recipient obesity on patient and graft survival after renal transplantation have demonstrated more mixed results. Several relatively small studies have demonstrated no significant adverse effect of recipient obesity on patient and graft survival.…”

mentioning

confidence: 99%

The Impact of Recipient Obesity on Outcomes After Renal Transplantation

Cannon

Jones²,

Hughes³

et al. 2013

Annals of Surgery

102

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High Body Mass Index and Posttransplant Weight Gain Are Not Risk Factors for Kidney Graft and Patient Outcome

Cited by 42 publications

References 9 publications

Evaluation of Nutritional Status in Renal Transplant Recipients in Accordance with Changes in Graft Function

Evaluation of Nutritional Status in Renal Transplant Recipients in Accordance with Changes in Graft Function

Higher recipient body mass index is associated with post-transplant delayed kidney graft function

The Impact of Recipient Obesity on Outcomes After Renal Transplantation

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