High baseline perivascular space volume in basal ganglia is associated with attention and executive function decline in Parkinson's disease
Ryan Patrick Foreman,
Erin Kaye Donahue,
Jared Joshua Duran
et al.
Abstract:BackgroundPathologic perivascular spaces (PVS), the fluid‐filled compartments surrounding brain vasculature, may underlie cognitive decline in Parkinson's disease (PD). However, whether this impacts specific cognitive domains has not been investigated.ObjectivesThis study examined the relationship of PVS volume at baseline with domain‐specific and global cognitive change over 2 years in PD individuals.MethodsA total of 39 individuals with PD underwent 3T T1w magnetic resonance imaging to determine PVS volume f… Show more
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