High Area Deprivation Index is Associated With Not Achieving the Patient-acceptable Symptom State After TKA

Abstract

Background The Area Deprivation Index (ADI) approximates a patient’s relative socioeconomic deprivation. The ADI has been associated with increased healthcare use after TKA, but it is unknown whether there is an association with patient-reported outcome measures (PROMs). Given that a high proportion of patients are dissatisfied with their results after TKA, and the large number of these procedures performed, knowledge of factors associated with PROMs may indicate opportunities to provide support to patients who might benefit from it. Questions/purposes (1) Is the ADI associated with achieving the minimum clinically important difference (MCID) for the Knee Injury and Osteoarthritis Outcome Score (KOOS) for pain, Joint Replacement (JR), and Physical Function (PS) short forms after TKA? (2) Is the ADI associated with achieving the patient-acceptable symptom state (PASS) thresholds for the KOOS pain, JR, and PS short forms? Methods This was a retrospective study of data drawn from a longitudinally maintained database. Between January 2016 and July 2021, a total of 12,239 patients underwent unilateral TKA at a tertiary healthcare center. Of these, 92% (11,213) had available baseline PROM data and were potentially eligible. An additional 21% (2400) of patients were lost before the minimum study follow-up of 1 year or had incomplete data, leaving 79% (8813) for analysis here. The MCID is the smallest change in an outcome score that a patient is likely to perceive as a clinically important improvement, and the PASS refers to the threshold beyond which patients consider their symptoms acceptable and consistent with adequate functioning and well-being. MCIDs were calculated using a distribution-based method. Multivariable logistic regression models were created to investigate the association of ADI with 1-year PROMs while controlling for patient demographic variables. ADI was stratified into quintiles based on their distribution in our sample. Achievement of MCID and PASS thresholds was determined by the improvement between preoperative and 1-year PROMs. Results After controlling for patient demographic factors, ADI was not associated with an inability to achieve the MCID for the KOOS pain, KOOS PS, or KOOS JR. A higher ADI was independently associated with an increased risk of inability to achieve the PASS for KOOS pain (for example, the odds ratio of those in the ADI category of 83 to 100 compared with those in the 1 to 32 category was 1.34 [95% confidence interval 1.13 to 1.58]) and KOOS JR (for example, the OR of those in the ADI category of 83 to 100 compared with those in the 1 the 32 category was 1.29 [95% CI 1.10 to 1.53]), but not KOOS PS (for example, the OR of those in the ADI category of 83 to 100 compared with those in the 1 the 32 category was 1.09 [95% CI 0.92 to 1.29]). Conclusion Our findings suggest that social and economic factors are associated with patients’ perceptions of their overall pain and function after TKA, but such factors are not associated with patients’ perceptions of their improvement in symptoms. Patients from areas with higher deprivation may be an at-risk population and could benefit from targeted interventions to improve their perception of their healthcare experience, such as through referrals to nonemergent medical transportation and supporting applications to local care coordination services before proceeding with TKA. Future research should investigate the mechanisms underlying why socioeconomic disadvantage is associated with inability to achieve the PASS, but not the MCID, after TKA. Level of Evidence: Level III, therapeutic study.

CORR Insights®: High Area Deprivation Index is Associated With Not Achieving the Patient-acceptable Symptom State After TKA

“…Although the work of Hadad et al [4] represents an important step in the journey to better understanding the many factors that affect our patients and procedures like TKA, there is much more to do. Since as many as 20% of our patients who undergo TKA aren't satisfied with the outcome, further research into the impact of the factors under our control and those outside of our control is needed.…”

“…Published in this issue of Clinical Orthopaedic and Related Research ® , Hadad et al [4] studied a relatively large retrospective cohort of patients who underwent TKA within a tertiary health system in two states. The authors found that increased socioeconomic disadvantage as determined by the ADI was associated with not achieving the patient-acceptable symptom state (PASS) thresholds for the Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain and KOOS JR. Interestingly, other PROMs and satisfaction were not associated ADI in the studied patient population.…”