High adherence to subcutaneous immunotherapy in a real-life study from a large tertiary medical center

Gelincik, Aslı; Demir, Semra; Olgaç, Müge; İşsever, Halim; Khishigsuren, Bayerma; Özşeker, Ferhan; Çolakoğlu, Bahaüddin; Büyüköztürk, Suna

doi:10.2500/aap.2017.38.4091

Cited by 19 publications

(58 citation statements)

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“…A close relationship between allergists and their patients during SCIT had great potential to affect the concordance levels of SCIT. 26 In Sanchez's 27 study, health education and follow-ups of patients were strictly carried out by medical staff, and the results showed a significant improvement in patient compliance(11% vs 21%, P=0.02). Savi et al 28 achieved an increased level of compliance by providing educational sessions for patients and conducting regular follow-up with patients by email or telephone.…”

Section: Discussionmentioning

confidence: 99%

<p>Interactive Network Platform Improves Compliance and Efficacy of Subcutaneous Immunotherapy for Patients with Allergic Rhinitis</p>

Shen

Tan

Zhong

et al. 2019

PPA

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Background: Allergic rhinitis (AR) is a common chronic inflammatory disease of nasal mucosa worldwide, and its symptoms seriously affect the lives of patients. Subcutaneous immunotherapy (SCIT) is an effective treatment for AR, but it is also associated with low patient compliance and difficulties in fully achieving therapeutic effects. Objective: In this prospective randomized controlled study, we verified the effects of an interactive network platform named "U breath" in improving patient compliance and the efficacy of SCIT in patients with AR. Methods: A total of 148 patients who received SCIT were recruited as participants and randomly assigned to either the standardized management (SM) or the interactive network platform management (INP) group. The SM group experienced the standard management SCIT process. The INP group experienced a new management approach based on an interactive network platform called "U breath". The compliance rate, combined symptom and medication score (CSMS), visual analogue scale score and the rhinoconjunctivitis quality of life questionnaire (RQLQ) results were evaluated at baseline and 1-year postintervention for the two groups. Results: Within the first year of treatment, the INP group had a higher compliance rate than did the SM group, with a statistically significant difference (P<0.05). The INP group showed better clinical improvement than the SM group did in terms of the VAS score, and the RQLQ score except the sleep problems (P< 0.05). Conclusion: This study confirmed that the application of an interactive network platform is of great significance for improving patient compliance and the treatment effects of SCIT in patients with AR.

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Section: Discussionmentioning

confidence: 99%

<p>Interactive Network Platform Improves Compliance and Efficacy of Subcutaneous Immunotherapy for Patients with Allergic Rhinitis</p>

Shen

Tan

Zhong

et al. 2019

PPA

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“…The most investigated was adherence and compliance, which was the subject of 5 studies (15,18,26,30). In a short-term study on SCIT, 87.2% of patients were considered adherent (15), while in a 3-year study the adherence at the last year was 64.66% (18). In the two 3-years studies on adherence to SLIT, the same outcome was reported, 55% of patients completing the entire treatment (26,30).…”

Section: Other Issues Investigatedmentioning

confidence: 98%

“…The results showed that SLIT approximately halved the symptom-medication scores compared to the score registered in drug-treated patients. Since then, several real-life studies were performed, including 11 studies on SCIT (7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17), 15 on SLIT (6,(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29) and 5 on both (30-…”

Section: Real-life Studies On Aitmentioning

confidence: 99%

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Allergic reactions after vaccination: translating guidelines into clinical practice

Incorvaia

Barberi

Pastorello

et al. 2019

Eur Ann Allergy Clin Immunol

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Real-life studies offer the opportunity of obtaining outcomes suitable in clinical practice, as controlled trials do not mirror the real patients' population observed in clinical practice. This concept is particularly appropriate for allergen immunotherapy (AIT). Therefore, the current review will present and discuss the most recent and relevant studies published on this topic. Globally, 15 real-life studies on AIT efficacy are available until now, the total of patients amounts to 9090, with an average number of 699 patients per study. This high number significantly decreases the possibility that the observations from real-life study are casual, and confers to such studies a key role in the next years to assess issues other than efficacy and safety, especially those scantly investigated thus far.sessed by meta-analyses, but the validity and applicability of the observations resulting from RCTs data, especially in the context of real-life settings, is debatable (5). To confirm the applicability to common practice of AIT products demonstrated as effective in RCTs, real-life (also defined real-world) studies are needed. This model was increasingly used in recent years and, especially when based on large populations of patients, provides very useful data to optimize the prescription and the performance of AIT in clinical practice. Here, we will discuss the significance of the outcomes that were achieved in such studies.

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“…In this issue, Gelincik et al 9 reported finding a high level of adherence to subcutaneous immunotherapy in a reallife study from a large tertiary medical center in Turkey. The authors indicated that a close relationship between allergists and their patients during allergy immunotherapy improved therapeutic outcomes.…”

mentioning

confidence: 99%

Hereditary angioneurotic edema … a disease has been described

Bellanti¹,

Settipane²

2017

allergy asthma proc

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High adherence to subcutaneous immunotherapy in a real-life study from a large tertiary medical center

Abstract: The adherence rate to SCIT in our study was relatively high, in contrast to previous real-life data. Results of our study indicated that a close relationship between allergists and their patients during SCIT and the follow-up period in the same center improved the outcome of SCIT.

Cited by 19 publications

References 0 publications

<p>Interactive Network Platform Improves Compliance and Efficacy of Subcutaneous Immunotherapy for Patients with Allergic Rhinitis</p>

<p>Interactive Network Platform Improves Compliance and Efficacy of Subcutaneous Immunotherapy for Patients with Allergic Rhinitis</p>

Allergic reactions after vaccination: translating guidelines into clinical practice

Hereditary angioneurotic edema … a disease has been described

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