High accuracy patient-specific 3D coronary reconstruction from angiography and intravascular optical coherence tomography

Abstract

The integration of digital subtraction angiography (DSA) with intravascular optical coherence tomography (IVOCT) offers a comprehensive 3D arterial model, which is invaluable for the analysis of vascular anatomy and biomechanics. However, the process of image fusion is often hindered by the challenge of accurately orienting IVOCT images. This paper introduces a novel, to our knowledge, dual-path 3D reconstruction method that leverages the guidewire and the vessel’s centerline to establish cross sectional direction vectors within the IVOCT images and spatial direction vectors along the guidewire’s trajectory. This approach minimizes the accumulation of reconstruction errors by ensuring the precise orientation of each vascular cross section. The efficacy of the proposed method is validated through vascular phantom experiments and the reconstruction of patient-specific 3D coronary models.