Hierarchically Organized Systems Based on Liquid Crystalline Phases

Kulkarni, Chandrashekhar V.; Glatter, Otto

doi:10.1002/9781118336632.ch6

Cited by 11 publications

(37 citation statements)

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“…Surfactant based stabilizers are more popular but solid particles have also been exploited with a varying level of success [26]. Emulsions stabilized by solid particles are termed generally as Pickering [32] or Ramsden-Pickering [33] emulsions.…”

Section: Introductionmentioning

confidence: 99%

“…The general term 'isasomes' meaning internally self-assembled particles (somes) is also often used in this context [26,27,29]. These emulsions exhibit a water-like fluidity desired for a range of high-throughput application including carrier systems for pharmaceutical and biomedical technologies [26,27,30,31]. molecules self-assemble into cubic nanostructure (Pn3m phase) which is fragmented into sub-micron sized particles that are stabilized using the F127 stabilizer [20].…”

Section: Introductionmentioning

confidence: 99%

“…Depending on the type of internal selfassembly, the nanostructured emulsions are recognized as cubosomes for cubic nanostructures, hexosomes for hexagonal nanostructures and so on [15,[26][27][28]. The general term 'isasomes' meaning internally self-assembled particles (somes) is also often used in this context [26,27,29]. These emulsions exhibit a water-like fluidity desired for a range of high-throughput application including carrier systems for pharmaceutical and biomedical technologies [26,27,30,31].…”

Section: Introductionmentioning

confidence: 99%

“…A wide range of stabilizers are employed for stabilizing aforementioned lipid nanoparticle emulsions [26]. Surfactant based stabilizers are more popular but solid particles have also been exploited with a varying level of success [26].…”

Section: Introductionmentioning

confidence: 99%

“…Structural organization of lipid self-assemblies in the bulk (non-dispersed form) and emulsions (dispersed form) is usually determined using small angle X-ray scattering (SAXS) and transmission electron microscopy (TEM) techniques [23][24][25]. Depending on the type of internal selfassembly, the nanostructured emulsions are recognized as cubosomes for cubic nanostructures, hexosomes for hexagonal nanostructures and so on [15,[26][27][28]. The general term 'isasomes' meaning internally self-assembled particles (somes) is also often used in this context [26,27,29].…”

Section: Introductionmentioning

confidence: 99%

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Effect of fullerene on the dispersibility of nanostructured lipid particles and encapsulation in sterically stabilized emulsions

Kulkarni

Moinuddin

Agarwal

2016

Journal of Colloid and Interface Science

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Abstract:We report on the effect of fullerenes (C60) on the stability of nanostructured lipid emulsions. These (oil-in-water) emulsions are essentially aqueous dispersions of lipid particles exhibiting self-assembled nanostructures at their cores. The majority of previous studies on fullerenes were focused on planar and spherical lipid bilayer systems including pure lipids and liposomes. In this work, fullerenes were interacted with a lipid that forms nanostructured dispersions of nonlamellar self-assemblies. A range of parameters including the composition of emulsions and sonication parameters were examined to determine the influence of fullerenes on in-situ and prestabilized lipid emulsions. We found that fullerenes mutually stabilize very low concentrations of lipid molecules, while other concentration emulsions struggle to stay stable or even to form at first instance; we provide hypotheses to support these observations. Interestingly though, we were able to encapsulate varying amounts of fullerenes in sterically stabilized emulsions. This step has a significant positive impact, as we could effectively control an inherent aggregation tendency of fullerenes in aqueous environments. These novel hybrid nanomaterials may open a range of avenues for biotechnological and biomedical applications exploiting properties of both lipid and fullerene nanostructures.

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Section: Introductionmentioning

confidence: 99%