Hierarchical Nanobiosensors at the End of the SARS-CoV-2 Pandemic

Abstract

Nanostructures have played a key role in the development of different techniques to attack severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some applications include masks, vaccines, and biosensors. The latter are of great interest for detecting diseases since some of their features allowed us to find specific markers in secretion samples such as saliva, blood, and even tears. Herein, we highlight how hierarchical nanoparticles integrated into two or more low-dimensional materials present outstanding advantages that are attractive for photonic biosensing using their nanoscale functions. The potential of nanohybrids with their superlative mechanical characteristics together with their optical and optoelectronic properties is discussed. The progress in the scientific research focused on using nanoparticles for biosensing a variety of viruses has become a medical milestone in recent years, and has laid the groundwork for future disease treatments. This perspective analyzes the crucial information about the use of hierarchical nanostructures in biosensing for the prevention, treatment, and mitigation of SARS-CoV-2 effects.

Development of Optical Differential Sensing Based on Nanomaterials for Biological Analysis

“…These materials improve signal intensity and enhance various energy transfer processes. The integration of hierarchical nanomaterials alongside other nanomaterials expands the design possibilities of analysis arrays, enabling even more diverse and efficient biosensing platforms [190]. Overall, the application of nanomaterials has dramatically improved the sensitivity and recognition range of pattern recognition detection, leading to more diverse array designs [191].…”