Hierarchical Integration of Curcumin‐Loaded CaCO3 Nanoparticles and Black Phosphorus Nanosheets in Core/Shell Nanofiber for Cranial Defect Repair
Yan Zheng,
Lu Tan,
Hang Chen
et al.
Abstract:Reconstruction and healing of large craniofacial bone defects are major clinical challenges due to high risk of chronic inflammation and reduced cell mineralization levels. Herein, a core‐shell nanofiber‐based implant with significant pro‐osteogenesis capability for treating skull defects is reported, which is hierarchically integrated with curcumin‐loaded calcium carbonate nanoparticles (CaCO3@Cur NPs) in the outer layers and black phosphorus nanosheets (BPNSs) in the core compartments. The radical alignment … Show more
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