Hidradenocarcinoma

Lima, Andrey Amorim de; Santos, Mônica; Morais, Patrícia Motta de; Rodrigues, Carlos Alberto Chirano

doi:10.1016/j.abd.2020.03.023

Cited by 9 publications

(9 citation statements)

References 5 publications

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“…Squamous cell cancer, basal cell carcinoma, metastatic clear cell carcinoma of the lungs and kidneys, dermatofibrosarcoma, eccrine porocarcinoma, and eccrine ductal carcinoma were the differential diagnoses under investigation [ 1 , 7 , 8 ]. The histological evaluation of such swellings is crucial to determine the prognosis.…”

Section: Discussionmentioning

confidence: 99%

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Hidradenocarcinoma of the Left Knee in a 55-Year-Old Woman: A Case Report

Ghaffari¹,

Saleem²,

Zahoor³

et al. 2022

Cureus

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The occurrence and scientific reporting of benign adnexal tumors arising from the eccrine and apocrine sweat glands, hair follicles, and pilosebaceous components of the skin is very rare. Even though they are uncommon, these long-standing benign lesions can transform into their malignant counterparts, which can be exceedingly difficult to treat because malignant lesions are linked to higher rates of morbidity and mortality. Here, we present a rare instance of primary hidradenocarcinoma of the left knee in a 55-year-old lady.

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Section: Discussionmentioning

confidence: 99%

“…Hidradenocarcinoma is a rare malignant adnexal tumor that arises from eccrine sweat glands, accounting for 6% of all malignant eccrine tumors [ 1 ]. The most common site of origin is the head and neck region, with rarer cases presenting in the extremities [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Hidradenocarcinoma of the Left Knee in a 55-Year-Old Woman: A Case Report

Ghaffari¹,

Saleem²,

Zahoor³

et al. 2022

Cureus

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“…(Elbenaye et al, 2017;Soni et al, 2015) In the literature, recurrence rates and metastasis rates have been reported as over 50%, and in our 6-month follow-up, no significant findings and radiological images were found in terms of metastasis and recurrence. (de Lima et al, 2021) In empirical treatment, wide resection is considered first. (Elbenaye et al, 2017;Soni et al, 2015) However, in our case, we performed total resection because we did not consider a malignant skin appendage tumor in the preliminary diagnosis.…”

Section: Discussionmentioning

confidence: 99%

“…Although there is no typical localization, it is seen in the literature that it is described on the lip, neck, back, chest wall, breast, vulva, and scalp. It is known to be more common in the age range of 50-60 years (de Lima et al, 2021;Elbenaye et al, 2017). These tumors have a high recurrence rate of 50-75%.…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Scalp Mass: Clear Cell Hidradenocarcinoma

KURTULUŞ¹,

TOKMAK

DİNÇ

et al. 2022

Black Sea Journal of Health Science

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Clear cell hydroadenocarcinoma is a very rare sweat gland tumor. It has an aggressive course and has a high recurrence rate. Wide excision is the first option in the treatment of this tumor with a high rate of metastasis. Subsequent radiotherapy and chemotherapy are still controversial. In this case, we presented a patient who was operated on and presented with a lipoma-like appearance on the scalp. The pathology result of the patient was Clear cell hidradenocarcinoma. We emphasized that in operations performed with the preliminary diagnosis of lipoma on the scalp, this diagnosis should be included among the preliminary diagnoses and resection should be performed as widely as possible.

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“…According to histological classification, the recognized variants include nodular hidradenocarcinoma, malignant acrospiroma, malignant clear-cell hidradenoma, and clear-cell eccrine carcinoma [1]. Local and frequent recurrences are common in the natural course of these tumors [4]. The involvement of regional lymph nodes and the presence of distant metastases are associated with a poor prognosis.…”

Section: Introductionmentioning

confidence: 99%

Malignant Transformation of Retroauricular Hidradenoma in Hidradenocarcinoma in a Nine-Year-Old Patient: A Case Report

Zorro¹,

Matias²,

Sousa³

et al. 2023

Cureus

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Hidradenocarcinoma, a rare malignant entity that derives from sweat glands, is especially rare in the pediatric population. The treatment of choice is surgery. Radiation therapy is used only in selected patients. Chemotherapy is not used extensively because its effectiveness has not been demonstrated yet.This case report describes a nine-year-old female patient who presented in 2018 with a vegetative lesion in the right parietal region. After excisional surgery, pathology confirmed that the lesion was a benign hidradenoma. However, the lesion recurred six months later, and subsequent surgery revealed nodular hidradenoma with positive margins. In July 2019, a new heterogenous lesion appeared in the right retroauricular region, which was surgically removed. The pathology report found possible malignant characteristics, and the patient was referred to our hospital where she was diagnosed with poorly differentiated right retroauricular carcinoma with infiltrative and perineural permeation, along with homolateral lymph node metastasis. It was histologically compatible with a hidradenocarcinoma. The patient underwent a wide-margin excision and homolateral total cervical lymphadenectomy, followed by adjuvant radiotherapy. The last follow-up MRI was negative for disease recurrence or metastasis; however, a slow-growing node on the left jugular chain (level II) was noted. The patient is on regular follow-ups to monitor disease status and treatment-related adverse events. This case highlights the challenges of diagnosing and treating hidradenocarcinoma, a rare malignancy that requires aggressive management with a multidisciplinary approach. More robust clinical evidence is needed to define the best treatment approach for these aggressive tumors.

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Hidradenocarcinoma

Cited by 9 publications

References 5 publications

Hidradenocarcinoma of the Left Knee in a 55-Year-Old Woman: A Case Report

Hidradenocarcinoma of the Left Knee in a 55-Year-Old Woman: A Case Report

A Rare Case of Scalp Mass: Clear Cell Hidradenocarcinoma

Malignant Transformation of Retroauricular Hidradenoma in Hidradenocarcinoma in a Nine-Year-Old Patient: A Case Report

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