Hidradenitis suppurativa: bacteriological study in surgical treatment

Abstract

Introduction: Hidradenitis suppurativa (HS) is an inflammatory chronic disease of the hair follicles that presents with different lesions in the apocrine gland-bearing areas of the human body. There are many possible factors for HS. Acne inversa is not primarily considered to be an infectious disease. A variety of Gram-positive and Gramnegative bacteria have been found from the lesions sporadically. Aim: To assess the bacteriological profile of HS before surgical treatment. Material and methods: We collected specimens for aerobic microbiological testing from 18 patients before surgical treatment in our hospital. The specimens were obtained from abscesses, directly from skin fistulas, on day 1 of hospitalisation. Results: The most common bacteria in HS lesions were Staphylococcus aureus and Proteus mirabilis. In 4 patients we found multi-drug-resistant bacteria (MLSB, MRSA and A. baumannii). Conclusions: Long-term antibiotic treatment can cause multi-drug resistance in strains collected in HS lesions.

Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

“…Treatment with topical or systemic antibiotics is widely used as first-line therapy in the management of mild stages of the disease. In severe cases (Hurley II/III), surgical methods should be considered [ 1 , 13 , 14 ]. It has been proven that health-related quality of life significantly improves after surgical treatment [ 6 ].…”

“…During HS reconstructive surgery, the most problematic aspect is wound closure due to wide excision (very large excision wounds). Such cases require reconstructive techniques that are standard in such cases, such as skin flaps, skin grafts, or both [ 13 , 14 ]. Surgical reconstructive techniques for the treatment of HS are limited.…”

“…There is no ideal method of wound closure in HS surgery. Local skin flaps (rotational skin flaps) appear to be a good method in terms of tissue coverage; however, they can cause displacement of potentially diseased tissue, which can lead to recurrence (hidradenitis suppurativa) [ 13 , 14 ]. Skin flaps are associated with the possibility of greater scarring and the possibility of vascular complications, such as necrosis of the skin flap.…”

“…Skin flaps are associated with the possibility of greater scarring and the possibility of vascular complications, such as necrosis of the skin flap. Split-thickness skin grafts can result in inflexible contracture scars, which can cause contractures, for example, in the armpits [ 14 , 15 ].…”

Sexual Dysfunction and Quality of Life in Patients with Hidradenitis Suppurativa and Their Partners

“…When the disease is uncontrolled, it may progress causing tissue damage, with scarring and fistulae, and uncomfortable symptoms such as pain, suppuration, unpleasant odor and pruritus [3,4]. The etiopathogeneses of HS seems to be multifactorial, but this is not completely understood [5][6][7]. HS was originally only regarded as a cutaneous disorder, but today, a growing body of evidence links HS with several dermatological and nondermatological comorbidities, such as metabolic syndrome, inflammatory bowel disease, cardiovascular risk, depression or anxiety, among others [8][9][10][11][12].…”