“…This fact was confirmed in the work of Marzano et al ( 20 ), which showed an inverse relationship between therapeutic delay and clinical response to medication in HS. Recent studies have also demonstrated the efficacy of ustekinumab in cases of HS ( 21 , 22 ). It should be remembered that there are treatments for HS that should be based on the severity of the disease, and other medications such as clindamycin, rifampicin, hormonal therapies, and association with various surgical approaches can be used, from incision and drainage to control infectious foci to extensive resections to remove irreversible lesions.…”