2021
DOI: 10.18700/jnc.200018
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Hiccups in neurocritical care

Abstract: Hiccup or hiccough is known by the medical term "singultus," which is a derivative of the Latin word "singult, " meaning "a gasp" or "a sob" [1]. Hiccups are characterized by involuntary, intermittent, repetitive, myoclonic, and spasmodic contractions of the diaphragm and the inspiratory intercostal muscles, leading to an abrupt and early closure of the glottis, terminating inspiration and generating the characteristic "hic" sound [2,3]. Both healthy adults and children commonly experience hiccup spells. In th… Show more

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Cited by 9 publications
(11 citation statements)
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“…The lateral medullary syndrome is frequently associated with central hiccups however, brainstem strokes often result in intractable hiccups lasting over months. 1 3 In our case, hiccups persisted for only 6–7 days and disappeared 4–5 days after initiating anticoagulant therapy for PE. The author also suggested the possibility of drug-induced chronic hiccups due to glucocorticoid usage as part of antiedema therapy.…”
mentioning
confidence: 49%
“…The lateral medullary syndrome is frequently associated with central hiccups however, brainstem strokes often result in intractable hiccups lasting over months. 1 3 In our case, hiccups persisted for only 6–7 days and disappeared 4–5 days after initiating anticoagulant therapy for PE. The author also suggested the possibility of drug-induced chronic hiccups due to glucocorticoid usage as part of antiedema therapy.…”
mentioning
confidence: 49%
“…Nonetheless, one patient had a singular episode. This could be attributable to Vagus nerve irritation secondary to pharyngeal and glottic stimulation during orotracheal intubation [ 24 ]. Another patient presented a pattern of hydrostatic pulmonary edema in the chest x-ray, associated with a positive fluid balance of 1586 cc and urinary output of 0.38 cc/kg/hour.…”
Section: Resultsmentioning
confidence: 99%
“…Hiccups are usually considered benign as they are self-limited with spontaneous resolution. However, if persistent for more than 48 hours, it can be the result of more threatening etiologies [ 9 ], which include meningitis, encephalitis, stroke, and central nervous system tumors that affect the central component. Afferent and efferent components can be stimulated to cause hiccups in the presence of mediastinal tumors, gastroesophageal reflux disease, esophageal tumors, or induced by drugs like steroids, anti-parkinsonian drugs, and antipsychotic medications.…”
Section: Discussionmentioning
confidence: 99%