1979
DOI: 10.1111/j.1464-410x.1979.tb03594.x
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Hibitane Bladder Irrigation in the Prevention of Catheter-associated Urinary Infection

Abstract: The effect of regular chlorhexidine bladder irrigations on catheter-induced urinary infection in patients admitted as urological emergencies was investigated. Excluding patients infected on admission the urine remained sterile throughout the period of catheterisation in 52% of those receiving chlorhexidine but in only 26% of a control group of patients.

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Cited by 29 publications
(8 citation statements)
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“…Although oral ingestion of chlorhexidine is usually well tolerated because negligible systemic absorption occurs, adverse effects can occur when large doses are ingested [35][36][37][42][43][44] fed formula prepared with chlorhexidine 0.05% (mistaken for sterile water), four developed oedema of the tongue and oral ulcers and one had acute pulmonary oedema 42 . An 80-year-old woman who accidentally ingested 10 g of chlorhexidine (200 ml of 5% solution) died after developing an acute respiratory distress syndrome 43 .…”
Section: Oral Ingestionmentioning
confidence: 99%
“…Although oral ingestion of chlorhexidine is usually well tolerated because negligible systemic absorption occurs, adverse effects can occur when large doses are ingested [35][36][37][42][43][44] fed formula prepared with chlorhexidine 0.05% (mistaken for sterile water), four developed oedema of the tongue and oral ulcers and one had acute pulmonary oedema 42 . An 80-year-old woman who accidentally ingested 10 g of chlorhexidine (200 ml of 5% solution) died after developing an acute respiratory distress syndrome 43 .…”
Section: Oral Ingestionmentioning
confidence: 99%
“…Although this method demonstrated some value in preventing UTI when an open drainage system was used, little overall benefit has been seen in studies with closed systems. [45][46][47][48][49] Infection control prin- ciples would dictate that unidirectional flow from the bladder to the drainage bag is best. Furthermore, in view of the potential for local toxic effects and the complexity of this method, antibacterial irrigation currently cannot be recommended.…”
Section: Bladder Irrigationmentioning
confidence: 99%
“…Garibaldi et al 82 Not an RCT SICT 83 Not an RCT Wewalka et al 84 Did not measure urinary infection Catheter flushing/solutions to bag Adesanya et al 85 Included patients with suprapubic catheters Davies et al 86 Long-term catheterisation Dille et al 87 Long-term catheterisation Dudley & Barriere 88 Not an RCT Giannoni et al 89 Not an RCT Holliman et al 90 Not an RCT Kirk et al 91 Publication data prior to review criteria Muncie et al 92 Long-term catheterisation Ruwaldt 93 Not an RCT and long-term catheterisation Sharpe et al 94 Not an RCT and outcomes not clearly stated Meatal care and nursing practice Crow et al 95 Not an RCT General…”
Section: Appendix I Inclusion Criteria Checklistmentioning
confidence: 98%