HFE hemochromatosis: influence of dietary iron intake on the iron overload of C282Y homozygous patients

Saliou, Philippe; Gac, Gérald Le; Mérour, Marie-Christine; Tripogney, Céline; Chanu, B; Gourlaouen, Isabelle; Nousbaum, Jean-Baptiste; Férec, Claude; Scotet, Virginie

doi:10.1007/s00277-015-2343-x

Cited by 2 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Further studies need to be done to analyze the clinical significance of a controlled diet based on HH severity and the degree of diet modification [17]. Hemochromatosis is a rare condition, contributing to the lack of large, randomized control trials.…”

Section: Discussionmentioning

confidence: 99%

Proposed dietary recommendations for iron overload: a guide for physician practice

Saleh¹,

Seaman²,

Palmer

2023

Current Opinion in Gastroenterology

View full text Add to dashboard Cite

Purpose of reviewIron overload disorders such as hemochromatosis involve unregulated absorption of dietary iron, leading to excessive iron accumulation in multiple organs. Phlebotomy is the standard of care for removal of excess iron, but dietary modification is not standardized in practice. The purpose of this article is to help standardize hemochromatosis diet counseling based on commonly asked patient questions. Recent findingsThe clinical benefit regarding dietary modification in iron overload patients is limited due to lack of large clinical trials, but preliminary results are promising. Recent studies suggest diet modification could reduce iron burden in hemochromatosis patients resulting in less annual phlebotomy as supported through small patient studies, concepts of physiology, and animal studies. SummaryThis article is a guide for physicians to counsel hemochromatosis patients based on commonly asked questions such as foods to avoid, foods to consume, use of alcohol, and use of supplements. The goal of this guide is to help standardize hemochromatosis diet counseling to reduce phlebotomy amount in patients. Standardization of diet counseling could help facilitate future patient studies to analyze the clinical significance.

show abstract

Section: Discussionmentioning

confidence: 99%