Heterozygosity in inbred lines of Tribolinm castaneum

Goodwill, R.E.; Enfield, F. D.

doi:10.1007/bf00279291

Cited by 6 publications

(11 citation statements)

References 4 publications

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“…Assuming a mean male: female ratio of 1/4 and an average of 45 females, the effective population size estimated by 4N m N f /(N m + N f ) is 36. This is similar to the estimate (N e = 30) that the authors provide without explanation (p. 11; Goodwill & Enfield, 1971). Accepting the latter estimate, the expected dynamics of genetic variance generated by equation (29) of Lynch & Hill (1986) yield an expected mean genetic variance over the 17 generations of selection of 10-5^.…”

Section: (Iii) Drosophila Adh Activitysupporting

confidence: 59%

“…Since the genes underlying Drosophila bristle numbers tend to be additive, the estimation of V m for this trait from the selection response does not seem inappropriate and indeed does not give greatly different results than divergence experiments (Table 1). However, given the results of Enfield et al (1966), it is possible that my estimate of V m for 21-day pupal weight in Tribolium using the selection results of Goodwill & Enfield (1971) may be inflated.…”

Section: Discussionmentioning

confidence: 87%

“…For the six data sets, I estimated var(vv) by h 2 V T and V E by (1-h 2 )V T . The average phenotypic standard deviations (VK) f o r l i n e s CSI-5 and CSI-10 over 17 generations are approximately 225 and 250 respectively (Figures 1 and 2; Goodwill & Enfield, 1971). The four estimates of V m /V B obtained for line CSI-10 (00100, 00100, 00134, O0183) are substantially higher than those for line CSI-5 (00028, 00000) for unknown reasons.…”

Section: (Iii) Drosophila Adh Activitymentioning

confidence: 98%

“…(iv) Tribolium pupal weight Goodwill & Enfield (1971) successfully selected for 21-day pupal weight in two highly inbred lines of Tribolium castaneum (CSI-5 and CSI-10). Prior to selection both lines had passed through 46 generations of single full-sib matings.…”

Section: (Iii) Drosophila Adh Activitymentioning

confidence: 99%

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The rate of polygenic mutation

1988

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By application of the neutral model of phenotypic evolution, quantitative estimates of the rate of input of genetic variance by polygenic mutation can be extracted from divergence experiments as well as from the response of an inbred base population to selection. The analytical methods are illustrated through a survey of data on a diversity of organisms including Drosophila, Tribolium, mice, and several crop species. The mutational rate of introduction of genetic variance (V m ) scaled by the environmental variance (V E ) is shown to vary between populations, species, and characters with a range of approximately 10~4 to 5 x 10" 2 . V m /V E for Drosophila viability is somewhat below this range, while hybrid dysgenesis may temporarily inflate V m /V E beyond 10" 1 . Potential sources of bias and error in" the estimation of V m are discussed, as are the practical implications of the observed limits to VJ V B for projecting the long-term response to selection and for testing adaptational hypotheses.

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Section: (Iii) Drosophila Adh Activitysupporting

confidence: 59%

Section: Discussionmentioning

confidence: 87%

Section: (Iii) Drosophila Adh Activitymentioning

confidence: 98%

Section: (Iii) Drosophila Adh Activitymentioning

confidence: 99%

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The rate of polygenic mutation

1988

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“…Several experimental studies have reported higher than predicted heterozygosities in inbred lines of chickens, Drosophila melanogaster, and Tribolium castaneum (Briles and McGibbon, 1948;Shultz and Briles, 1953;Gilmour, 1954Gilmour, , 1958Gilmour, , 1959Gilmour, , 1960Gilmour, , 1962Cock, 1956;Briles et ah, 1957;Goodwill and Enfield, 1971;Yeh and Scheinberg, 1972;Chapco et al, 1973;Rumball, 1974). Conversely, Morrow et al (1974) reported good agreement between observed and expected homozygosities for 10 blood groups in six highly inbred lines of chickens.…”

Section: Introductionmentioning

confidence: 94%

Heterozygosity at Protein Loci in Inbred and Outbred Lines of Chickens

et al. 1991

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Levels of heterozygosity at six polymorphic protein marker loci were determined by electrophoresis in 24 lines of poultry, encompassing 17 White Leghorn inbred lines (WLI) (with inbreeding coefficients, F, ranging from .946 to .988), five Australorp inbred lines (AusI) (with F values ranging from .924 to .961), and two randombred lines (one White Leghorn and one Australorp). Fixation was observed at one locus in WLI lines, and at two loci in the AusI lines. Segregation at the other loci was observed in the inbred lines of the two breeds. Observed heterozygosity in the inbred lines markedly exceeded the expectations under inbreeding theory. In White Leghorns, reproductive fitnesses for heterozygotes were superior to homozygotes in the inbred lines, but not in the control. Consequently, natural selection operating through associative overdominance appears to be responsible for the higher than expected heterozygosities in the inbred lines.

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Certain growth characters of Tribolium castaneum as modified by long term selection for 21-day pupa weight

Walker

Goodwill

1974

Theoret. Appl. Genetics

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Heterozygosity in inbred lines of Tribolinm castaneum

Cited by 6 publications

References 4 publications

The rate of polygenic mutation

The rate of polygenic mutation

Heterozygosity at Protein Loci in Inbred and Outbred Lines of Chickens

Certain growth characters of Tribolium castaneum as modified by long term selection for 21-day pupa weight

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