Heterotopic salivary tissue and branchial sinuses

Abstract

Heterotopic salivary tissue and branchial sinuses occur not infrequently (Goddman et al., 1981; Stingle and Priebe, 1974), caused probably by heteroplasia within remants of the second cleft (Stingle, 1974). Bilateral lesions which presented clinically as branchial cleft sinuses have been removed from a patient's neck; both of them proved to be branchial cleft sinuses with elements of slivary tissue.The paper describes sailvary tissue and branchial sinuses along the anterior border of the sternocleidomastoid muscle on both sides of the neck and bilateral preauricular fistulae occurring in a boy and probably in his sister.

Bilateral Cervical Fistulas from Heterotopic Salivary Gland Tissues

“…There were 9 bilateral cases [6,10,11,12,13,14,15,16]. A summary of these bilateral cases is presented in table 1.…”

“…We found two characteristics common to bilateral cases. The first is family history: 4 patients had a family history of some cervical anomalies [10,12]. Hsu et al [10] reported familial occurrence of HSGT, representing an autosomal dominant inheritance pattern.…”

“…The second characteristic is the presence of other congenital anomalies: 3 patients had other congenital anomalies [11,13]. Of those, 2 patients had abnormal auricles, preauricular pits, and middle or inner ear anomaly [11], while the other patient had craniofacial anomalies and many other anomalies throughout her body [12]. In reviewing reports of 39 unilateral cases, a family history of HSGT or congenital anomaly was present in only 1 case (auricular pits and a family history of HSGT) [11].…”

Branchial Cleft Fistula with Heterotopic Salivary Gland Tissue in the Lower Neck

“…tonsil, mandible, lower neck, hypopharynx, sternoclavicular joint or middle ear) [1], To our knowledge, only 23 cases of het erotopic salivary gland tissue in the neck have been reported up to 1986 [2,[6][7][8].…”

ecancermedicalscience

“…However, a primary connective tissue LELC could be assumed, based on the branchial embryonic remnants origin, particularly from branchial cysts arisen from the second branchial arch [21]. In fact, these cysts, consisting of lymphoid aggregates that can have either squamous or respiratory-type epithelial lining, occur mostly along the front edge of the sternocleidomastoid muscle from the plane passing through the hyoid bone to the suprasternal notch [21, 22, 23]. …”