Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993

Tal, J.; Haddad, Siham El; Gordon, Noam; Timor‐Tritsch, I. E.

doi:10.1016/s0015-0282(16)58378-2

Cited by 261 publications

(66 citation statements)

References 61 publications

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“…Tal and colleagues in a review reported that 70% of HPs are diagnosed between 5 and 8 weeks, 20% between 9th and 10th week and remaining 10% from 11th week [2]. The case reported falls in line with the 20% of people diagnosed between 9th and 10th week.…”

Section: Discussionmentioning

confidence: 66%

“…HP is thus rarely considered as a differential of first trimester bleeding following natural conception as was in our case, and thus likely to be missed [1, 8]. Furthermore, research shows that the main risk factors associated with ectopic pregnancy are tubal surgery and pelvic inflammatory disease [1, 2], which were nonexistent in our patient. The suspicion of HP in this patient was thus very unlikely.…”

Section: Discussionmentioning

confidence: 78%

“…It is a seldom but yet fatal condition whose diagnosis can easily be missed. Heterotopic pregnancies are thought to be caused by multiple ovulations; the incidence is thus expected to be higher amongst women with assisted reproductive techniques [2–4]. The incidence of HP in the general population is estimated to be 1 in 30,000.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Blighted ovum and tubal pregnancy: a rare form of heterotopic pregnancy: case report

Aroke¹,

Ngek

Tindong

et al. 2018

BMC Res Notes

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BackgroundHeterotopic pregnancies are rare in spontaneous conceptions. Nonetheless, when it does occur, the intrauterine pregnancy is usually viable. We herein present a true rarity of the coexistence of a blighted ovum and an ectopic pregnancy.Case presentationA 25 year old G2P1001 married seamstress of African ethnicity at 8 weeks of amenorrhoea presented to our health facility with a 4 day history of lower abdominal pains and vaginal bleeding for which physical examination revealed a closed cervix. Trans-abdominal ultrasound scan confirmed a diagnosis of a blighted ovum and an ectopic pregnancy. Patient was managed with surgical therapy. Evolution thereafter was uneventful.ConclusionThe case presented confirms that HP can occur in the absence of predisposing factors, and that the detection of a blighted ovum should not preclude the possibility of a simultaneous ectopic pregnancy. A high index of suspicion could lead to early diagnosis, prompt management and a favourable prognosis even in a low-income setting.

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Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 78%

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Blighted ovum and tubal pregnancy: a rare form of heterotopic pregnancy: case report

Aroke¹,

Ngek

Tindong

et al. 2018

BMC Res Notes

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“…With clomiphene citrate the incidence is 1 in 900 whereas with gonadotrophins it is 1%. 3 The most common predisposing anatomic finding associated with heterotopic pregnancies is preexisting tubal disease. 4 Abdominal pain, adnexal mass and an enlarged uterus constitute the major clinical features associated with a heterotopic pregnancy.…”

Section: Discussionmentioning

confidence: 99%

“…This is due to the fact that serial β-hCG determinations and transvaginal ultrasonography are often not helpful in establishing an early diagnosis. [3][4][5] And usually the delay is due to inability of treating clinician to think of a heterotopic pregnancy once an intrauterine gestation is established. 6 They are often confused with ruptured corpus luteum cyst.…”

Section: Discussionmentioning

confidence: 99%

Heterotopic pregnancy: case report of a successful first trimester metacyesis management and a viable third trimester outcome

Singh¹,

Khan²

2018

Int J Reprod Contracept Obstet Gynecol

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Heterotopic pregnancies are rare combined intra and extrauterine pregnancies, the incidence of which has shown an increase over the past decade with the rising trend in assisted reproductive technologies (0.75-1.5%). Authors report a case of a 29 year old primigravida, a post IVF conception who presented at 6 weeks POG with a ruptured tubal and a viable intrauterine pregnancy. She underwent an emergency laparoscopic right salpingectomy and continued with her intrauterine pregnancy successfully till term. The article emphasizes the need of scanning the adnexa carefully in early pregnancy to diagnose and manage heterotopic pregnancy as early as possible to prevent catastrophic haemorrhage and maternal morbidity and mortality later.

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Heterotopic pregnancy after IVF

Ramzy

2021

Assisted Reproduction Techniques

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Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993

Cited by 261 publications

References 61 publications

Blighted ovum and tubal pregnancy: a rare form of heterotopic pregnancy: case report

Blighted ovum and tubal pregnancy: a rare form of heterotopic pregnancy: case report

Heterotopic pregnancy: case report of a successful first trimester metacyesis management and a viable third trimester outcome

Heterotopic pregnancy after IVF

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