Heterotopic Pancreatic Tissue Involving the Stomach

Heterotopic Pancreas

“…Though all age groups may be affected, the highest incidence is in the 5th and 6th decades [2,6]. Most ectopic pancreatic glands are found incidentally at autopsy, during surgery or occasionally on routine radiographic studies.…”

“…[2] reported that 90% of 212 cases were found in the upper gastroin testinal tract -stomach (38%), duodenum (36%), and jejunum (16%), and this is consistent with most reported series. Eighty to 95 percent of ectopic pancreas occurring in the stomach were located in the antrum within 5-6 cm of the pylorus, usually located in the submucosa, but occasionally in the muscular layer and seldom in the serosa [1,6,11,12], In the duodenum, 80% were found in the second portion [3], Most jejunal ectopic pan creatic lesions are located in the proximal portion as found in our cases [2], Other rare sites of occurrence include the ileum, Meckel's diverticulum, omentum, ampulla of Vater. gallbladder, umbilicus, fallopian tube, mediastinal cyst, lung, spleen, and liver [1.…”

“…The typical gross clinical appearance of hetcrotopic pancreatic tissue is a small yellowish-white, round or oval shaped broad-based firm mass measuring 1-5 cm in diameter [6,11,12]. Radiologic findings show a smooth mucosa with a sharply demarcated filling defect of 1-3 cm in diameter with a central umbilication identified by a fleck of barium and described as a 'bulls eye' defect [11,18].…”

“…However, Kilman and Berk [ 19], studied radiologic findings of 20 cases and found that only 20% had a small barium collection in the central niche. The central depression of the mucosa is thought to be a duct system that communicates with the gastric lumen [6,11,20], Forty percent of cases have masses which appear more sessile than broad-based [19]. The endoscopic appear ance is similar to the radiologic findings.…”

Adenocarcinoma arising in association with gastric heterotopic pancreas: A case report and review of the literature

“…Adenocarcinoma arising within heterotopic pancreas appears to be a rare occurrence, with fewer than 30 cases being reported in the world literature [1,4,6,8,[13][14][15][17][18][19]21,23,24,[26][27][28][30][31][32]35,[37][38][39]. Nakao et al [30] reported a 12.7% incidence of cancer in cases of aberrant pancreas.…”