Heterotopic adrenal gland in undescendent testis – Case report

Zhou

et al. 2021

PAR

A case of ectopic adrenal gland tissue in mesosalpinx is reported. A 52-year-old patient was admitted to the hospital for irregular vaginal bleeding for 2 months. Ultrasound scan showed multiple hypoechoic masses in the myometrium of the anterior wall of uterus with regular shape and clear boundary. Laparoscopic hysterectomy and bilateral adnexectomy were performed. In the course of pathological diagnosis, we accidentally found ectopic adrenal gland tissue in the left mesosalpinx. We believe this is worthy of reporting since this case is rare.

Section: Discussionmentioning

confidence: 99%

Ectopic Adrenal Gland in Mesosalpinx: A Case Report and Literature Review

Zhou

et al. 2021

PAR

“…Ectopic adrenal gland tissue is located in a site other than the normal location of the adrenal gland. The development of adrenal glands occurred during the fourth and fifth weeks of gestation and comprises an adrenal cortex originating from the mesoderm and an adrenal medulla originating from the ectoderm [ 1 , 6 ]. During fetal development, the medullary tissue invades the cortex along the central vein, and small fragments from the defect migrated to the abnormal adrenal site becoming the ectopic adrenal gland [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…The third zone, or the reticularis, is composed of cells smaller than the fasciculate of the second layer, and this cytoplasm is lipid-free and is composed of granular and acidophilic cells. As the ectopic adrenal gland moves further than the existing adrenal gland location, only the cortex tends to remain among the components of the adrenal gland [ 6 , 7 ]. As a result of immunohistochemical analysis, positive for Melan-A and Inhibin-A and negative for AE1/AE3 is characteristic of this tissue [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…As the ectopic adrenal gland moves further than the existing adrenal gland location, only the cortex tends to remain among the components of the adrenal gland [ 6 , 7 ]. As a result of immunohistochemical analysis, positive for Melan-A and Inhibin-A and negative for AE1/AE3 is characteristic of this tissue [ 6 ]. According to the embryological theory described above, this tissue is frequently observed not only in the spermatic cord region but also in the celiac axis area, broad ligament, adnexa of testes, kidney, lung, and intracranial cavity [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

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Ectopic adrenal gland tissue in the left ovary of an elderly woman: case report

et al. 2021

Ectopic adrenal gland in the ovary is very rare case, and even more rarer in older women. We reported a case of ectopic adrenal tissue as an incidental finding in left ovary from a 68-year-old woman. She presented with bearing down sensation due to uterine prolapse for 5 years. Upon physical examination, uterine prolapse grade III, cystocele, and rectocele were observed. Ultrasonography findings showed 0.69 cm intramural myoma, and no specific findings were found in the bilateral adnexae. She underwent a total laparoscopic hysterectomy, bilateral salpingo-oophorectomy, and anterior-posterior repair. The final pathologic diagnosis of the case was ectopic adrenal gland tissue in the left ovary and uterine leiomyoma. No eventful reactions were observed during hospitalization and after discharge. Although ectopic adrenal gland rarely occurs in elderly women and in the pelvic ovaries, it has a risk of neoplastic transformation and accompanying germ cell tumor and sex cord tumor. Hence, if the ectopic adrenal gland tissue is suspected during surgery, the tissue should be removed. Additionally, by closely examining the contralateral ovary, determining whether other lesions are suspected is necessary. If the other lesions including germ cell tumor or sex cord tumor are suspected, a biopsy of the contralateral ovarian tissue should be performed. Thus, gynecologists must have knowledge about ectopic adrenal gland tissues.

“…Retroperitoneal adipose tissue and the kidneys are the usual recipients of ectopic adrenal tissue. In comparison, the ovary, testis, spermatic cord, liver, colon transversum, and gastric wall are rarely reported with adrenal heterotopia [1].…”

Section: Introductionmentioning

confidence: 91%

Adrenal Crest in Testicular Tissue of an Undescended Testis in an Adult Patient: A Case Report

Alzughaibi,

Alasiry,

Eid

et al. 2023

Cureus

This case report describes a rare occurrence of ectopic adrenal cortical tissue (EACT) in the undescended testis (UDT) of an adult male patient. The patient presented with an empty left scrotum since birth, and a magnetic resonance imaging (MRI) confirmed the diagnosis of left-side UDT. Orchidectomy was performed, and a microscopic examination revealed a UDT with EACT. The patient had no significant medical or surgical history and had a normal preoperative hormonal profile. EACT is usually found incidentally during surgical procedures and is more common in children than adults. This case emphasizes the importance of investigating adrenal rests due to the potential of neoplastic transformation or hormonal activity. The case report concludes that EACT of the UDT is still a possibility in the adult patient population.