Heterogeneous responses to embryonic critical period perturbations among different components of theDrosophilalarval locomotor circuit
Niklas Krick,
Jacob Davies,
Bramwell Coulson
et al.
Abstract:As developing neural circuits become functional, they undergo a phase of heightened plasticity in response to intrinsic and/or extrinsic stimuli. These developmental windows are termed critical periods (CPs), because perturbations during the CP can lead to lasting and significant change in subsequent development, such as sub-optimal and/or unstable networks. By contrast, the same manipulations before or after the CP does not create lasting changes. Here, we have used theDrosophilalarval locomotor network to st… Show more
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