Heterocyclic aromatic amines in cooked hamburgers and chicken obtained from local fast food outlets in the Ottawa region

The effects of conjugated linoleic acid usage in meatball production on the formation of heterocyclic aromatic amines

“…However, MeIQx content of the meatballs with and without CLA was generally similar to the values reported in the literature. Knize et al (1994) determined MeIQx at levels between nd-7.3 ng/g in beef fried at 150e230 C for 4e20 min; Klassen, Lewis, Lau, and Sen (2002) determined MeIQx levels between 0.3 and 0.34 ng/g in beef pan-fried at 160e220 C for 14 min. There are, however, other studies in which much higher MeIQx values have been identified.…”

Heterocyclic Amines in Several Types of Cooked Meat and Chicken Dishes which Form Part of the Korean Diet

“…Earlier reports have shown low levels of HAs in meat, beef and chicken (Klassen et al, 2002, Philippe et al, 2000, Sinha et al, 1998, Skog et al, 1998. The presence of MeIQx and PhIP has been reported in meat extract (2.3 and 1.5 ng g -1 , respectively), grilled beef (16.4 and 67.5 ng g -1 , respectively) and fried chicken (1.0 and 70.0 ng g -1 , respectively) (Skog et al, 1998).…”

Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: The role of ion pair reagents on LC–MS/MS sensitivity

“…In the last part of the study, the ammonium acetate (pH 4.0), usually employed in HAA chromatographic separation [5,7,14,17,18], was evaluated for the study of the amine retention by IPC and the results in terms of peak shape, analysis time and detectability of the analytes were compared with those obtained with the ammonium formate/formic acid buffer. The same eluent gradient as reported in Section 2 was run for both buffer solutions.…”

“…As regards to HPLC, separation of HAAs is commonly performed on a reversed-phase (RP) C 18 column [5][6][7][8][9][10][11][12][13][14][15]. However, a drawback of ordinary RPLC is that organic solute ions exhibit poor peak shapes and inadequate retention.…”

“…In the past few years many papers dealing with the analysis of these mutagenic compounds by LC coupled with mass spectrometry (MS) and tandem mass spectrometry (MS/MS) have been published [5,7,8,10,[12][13][14][15][16][17]. In most of these studies, LC has been performed under RP conditions using buffered mobile phases, salts used as buffers likely acting as ion-pair reagents.…”