“…To best of our knowledge, few cases were reported to have acquired Horner's syndrome with heterochromia in the literature. 4 , 5 , 6 With the exception of Diesenhouse's and Byrne's report, 7 , 8 most of these cases were acquired Horner's syndrome which developed in childhood. The researchers investigating congenital Horner's syndrome believe that the interruption of postganglionic pathway caused neurotropic diagenesis in the iris melanocytes.…”
PurposeTo present a case of iatrogenic Horner's syndrome seen together with the heterochromia in the post-thyroidectomy period.MethodsA 23-year-old female patient was admitted to our clinic with complaints of low vision in the eye and difference in eye color that developed over the past two years. In the left eye, myosis and minimal ptosis (∼1 mm) was detected, and the color of the iris was lighter than the right eye.ResultsThe pre-diagnosis of left iatrogenic Horner's syndrome was finalized after 0.5% topical apraclonidine test.ConclusionHeterochromia can be observed in iatrogenic Horner's syndrome.
“…To best of our knowledge, few cases were reported to have acquired Horner's syndrome with heterochromia in the literature. 4 , 5 , 6 With the exception of Diesenhouse's and Byrne's report, 7 , 8 most of these cases were acquired Horner's syndrome which developed in childhood. The researchers investigating congenital Horner's syndrome believe that the interruption of postganglionic pathway caused neurotropic diagenesis in the iris melanocytes.…”
PurposeTo present a case of iatrogenic Horner's syndrome seen together with the heterochromia in the post-thyroidectomy period.MethodsA 23-year-old female patient was admitted to our clinic with complaints of low vision in the eye and difference in eye color that developed over the past two years. In the left eye, myosis and minimal ptosis (∼1 mm) was detected, and the color of the iris was lighter than the right eye.ResultsThe pre-diagnosis of left iatrogenic Horner's syndrome was finalized after 0.5% topical apraclonidine test.ConclusionHeterochromia can be observed in iatrogenic Horner's syndrome.
“…Dentre as principais causas adquiridas de heterocromia iridiana, citam-se o corpo estranho intraocular, (34) o trauma ocular, (8,9) a SH adquirida tardiamente, (8,10,35) a oclusão da veia central da retina, a siderose, (11) o diabetes mellitus, os tumores benignos na íris, cistos ou abscessos, o melanoma ou nevo difuso da íris, (8,11,36) as irites ou uveítes, o uso unilateral tópico de um análogo da prostaglandina para o glaucoma, (8,11,35) a SUF (9,11) e a quimioterapia intravítrea. (37) Diversos agentes etiológicos que levam à uveíte podem promover uma irite heterocrômica, como a uveíte herpética, (9,35) incluindo o citomegalovírus associado à síndrome de Fuchs, (38) além do Ebolavirus (39) e do Rubella vírus associado à síndrome de Fuchs. (38) A melanocitose oculodermal (nevo de Ota) também é uma causa relatada de heterocromia de íris.…”
Section: Condições Adquiridasunclassified
“…Essa heterocromia pode ser observada em crianças menores de 2 anos de idade e na forma congênita, sendo incomum na SH adquirida. (66,68,69) A heterocromia na SH ocorre devido à redução do número de melanócitos da íris, mecanismo semelhante às modificações fisiológicas da cor dos olhos na idade adulta. A heterocromia é decorrente também da estimulação simpática que cursa com efeito trófico nos melanócitos da íris, cuja desnervação reduz o número de melanócitos, tanto na borda anterior quanto nas camadas estromais iridianas, tornando o olho afetado mais claro.…”
Section: Síndrome De Hornerunclassified
“…A heterocromia é decorrente também da estimulação simpática que cursa com efeito trófico nos melanócitos da íris, cuja desnervação reduz o número de melanócitos, tanto na borda anterior quanto nas camadas estromais iridianas, tornando o olho afetado mais claro. (1,69)…”
“…Iris heterochromia, caused by deficiency of sympathetic activity interfering with melanin pigmentation of the melanocytes in the superficial stroma of the iris, is described as one of the clinical features of congenital Horner syndrome. However, acquired Horner syndrome with iris heterochromia has been rarely reported (1–3). We contribute a unique case of adult-onset Horner syndrome with reversal of iris heterochromia as he had different iris colors from congenital iris heterochromia and subsequently changed into a similarly blue color in both eyes.…”
Iris heterochromia is typically seen in association with congenital Horner syndrome. A man in his 40s with congenital iris heterochromia, blue in the right and brown in the left, presented with left-sided Horner syndrome. This was associated with recent change in color of his brown left iris to blue similar to the right iris. This case demonstrates a unique case of adult-onset Horner syndrome with reversal of iris heterochromia.
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