Heterochromia of the Hair and Eyelashes with Blaschkoid Dyspigmentation

Abstract

Heterochromia of the hair involves the presence of two distinctive colors of scalp hair in one individual. We report the case of a 4-year-old girl with reddish streaks of scalp hair, heterochromia of the eyelashes, and cutaneous hypopigmentation following the lines of Blaschko.

A rare case of congenital red hair heterochromia of the scalp

“… 1 Segmental hair heterochromia describes alternating light and dark sections in each hair shaft and may occur with iron deficiency. 2 Diffuse scalp heterochromia describes hair of different colors evenly distributed over the entire scalp and may be associated with systemic conditions such as kwashiorkor or phenylketonuria with lighter hair color or with medications such as minoxidil causing hair darkening, diazoxide causing red hair, or chloroquine causing depigmented hair. 3 Rarely, diffuse hair heterochromia has been described in families, unrelated to any underlying causes.…”

“… 1 The cases described by Iorizzo et al 6 included a boy with circular band of lighter hair along the crown of the scalp and a girl with multiple bands of brown hair from the vertex whorl. 6 Dumitrascu et al 2 described a girl with reddish streaks of scalp hair, heterochromia of eyelashes, and cutaneous pigmentary mosaicim. The condition remains stable as the child grows.…”

Focal Scalp Hair Heterochromia in an Infant

“…2 Discrete patches of lighter or darker coloured hair with a Blaschkoid distribution may occur in rare cases. 3,4 Several reports of segmental hair heterochromia have been published in which demarcated variations in colour occur along a single hair shaft. 5,6 This variation usually takes the form of an intermittent loss of pigmentation.…”