Het Syndroom Van Lemierre: Een Gecompliceerde Orofaryngeale Infectiethe Lemierre Syndrome: A Complicated Orofaryngeal Infection

Libeer, C.; Bockaert, J.; Brande, P. Van den; Zachée, Pierre; Vyvere, M. Van De; Geyskens, W.

doi:10.1179/acb.2005.031

Cited by 1 publication

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“…7) but it was Lemierre who defined the clinical entity of the disease describing a series of 20 cases of throat infections with anaerobic septicemia in 1936. 2,8–10) …”

Section: Introductionmentioning

confidence: 99%

Lemierre Syndrome Associated with Ipsilateral Recurrent Laryngeal Nerve Palsy: A Case Report and Review

Miyamoto

Toi

Kotani

et al. 2016

NMC Case Report Journal

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Lemierre syndrome (LS) is a rare life-threatening disease that is often caused by an acute oropharyngeal infection with a secondary thrombophlebitis of the internal jugular vein. LS rarely manifests as cranial nerve palsy. To the best of our knowledge, this is the second case report of LS associated with recurrent laryngeal nerve palsy. A 66-year-old female presented to a dental clinic with gingivitis and sore throat. Due to moderate periodontitis, her left first upper molar was extracted. A few days later, she subsequently developed a coarse voice and occipital headaches, and was referred to an otolaryngologist. She was diagnosed with left recurrent laryngeal nerve palsy and subsequent left-sided otitis media, and was referred to us for persistent headaches. She intermittently presented with high-grade fever and complained of salty taste disturbance. Her head magnetic resonance imaging (MRI) revealed left mastoiditis, thrombosis in the left transverse and sigmoid sinus, and left internal jugular vein. Her laboratory tests revealed an elevated white blood cell count, levels of C-reactive protein, and D-dimer. No endogenous coagulopathy was confirmed. Although, blood and cerebrospinal fluid culture grew no microorganisms, respectively, the empirically determined antibiotic therapy was initiated. In a week, the patient defervesced and had no headaches despite persistent thrombosis. Early diagnosis and an immediate antibiotic treatment are crucial for LS patients. Anticoagulation therapy was not needed for our patient and is still controversial for LS.

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“…7) but it was Lemierre who defined the clinical entity of the disease describing a series of 20 cases of throat infections with anaerobic septicemia in 1936. 2,8–10) …”

Section: Introductionmentioning

confidence: 99%